DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and Ctsm

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_852043.2	Gene:	Ctsm / 306720	RGDID:	631420	Length:	333	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	109/313 - (34%)
Similarity:	161/313 - (51%)	Gaps:	28/313 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 KVYSDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEFGER 111
            |.||.||...:.:::...|..|.|.|.....|..||.:.:|...|||           |.||.:.
  Rat    38 KTYSLEEEGQKRAVWEENMKKIKLHNGENGLGKHGFTMEMNAFGDMT-----------IEEFRKL 91

  Fly   112 YTNGHINFVTARNPA----SANLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRT 172
            .....|..|...|..    :.|:|...:||::|.|||...|| .|..||:|:..||:||.:|::|
  Rat    92 MIEIPIPTVKKENSVQKRQAVNVPNFINWRKRGYVTPVRRQG-RCNVCWAFSVAGAIEGQMFQKT 155

  Fly   173 GVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDH-GVTLANKYPYTQTEMQCRQNETAGRP 236
            |.|..||.||||||:...||:||..|......:|:::: |:.....|||.:.|..||.:
  Rat   156 GQLIPLSVQNLVDCSRPQGNLGCYLGNTYLALQYVKENGGLESEATYPYEEKEGSCRYH------ 214

  Fly   237 PRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSV 301
            |..|...|.|:..: |.:|:.:...:|||||::.:::|...||..|..|||.:..|:...:.|::
  Rat   215 PDNSTASITDFEFV-PKNEDALMNAVATLGPISVAIDARHESFLFYRNGIYHEPNCSSSVVTHAM 278

  Fly   302 TVVGYG----TENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYP 350
            .:||||    ..:||.|||:|||....||..|:|:|.::.|..||||:...||
  Rat   279 LLVGYGFVGEESDGRKYWILKNSMGNKWGNRGYMKIAKDQGNHCGIATYALYP 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	16/49 (33%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	84/223 (38%)
Ctsm	NP_852043.2	Inhibitor_I29	29..87	CDD:214853	17/59 (29%)
Ctsm	NP_852043.2	Peptidase_C1A	115..331	CDD:239068	84/223 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830