Protein Alignment CtsL2 and Ctsk

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_113748.1
• Gene: Ctsk / 29175
• RGDID: 61810
• Length: 329
• Species: Rattus norvegicus
• Alignment Length: 348
• Identity: 125/348 - (35%)
• Similarity: 192/348 - (55%)
• Gaps: 25/348 - (7%)

  Fly     7 MWLQMTLGLALLGAVSLQQLQSFPKLCDVQNFDDFLRQTGKVYSDE-ERVYRESIFAAKMSLITL 70
            ||:...|   ||..||.  ..|..:..|.| ::.:.:..||.|:.: :.:.|..|:...:..|::
  Rat     1 MWVFKFL---LLPVVSF--ALSPEETLDTQ-WELWKKTHGKQYNSKVDEISRRLIWEKNLKKISV 59

  Fly    71 SNKNADNGVSGFRLGVNTLADMTRKEIA-TLLGSKISEFGERYTNGHINFVTARNPA-SANLPEM 133
            .|..|..|...:.|.:|.|.|||.:|:. .:.|.::.. ...::|.     |...|. ...:|:.
  Rat    60 HNLEASLGAHTYELAMNHLGDMTSEEVVQKMTGLRVPP-SRSFSND-----TLYTPEWEGRVPDS 118

  Fly   134 FDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGG 198
            .|:|:||.|||...|| .||:||:|::.|||||.|.::||.|.:||.||||||..:  |.||.||
  Rat   119 IDYRKKGYVTPVKNQG-QCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSE--NYGCGGG 180

  Fly   199 FQEYGFEYIRDH-GVTLANKYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVI 262
            :....|:|::.: |:...:.|||...:..|..|.||      ...|.|.|..|..|:|:.:|..:
  Rat   181 YMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATA------KAAKCRGYREIPVGNEKALKRAV 239

  Fly   263 ATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVVGYGTENGRDYWIIKNSYSQNWGE 327
            |.:||::.|::|...||:.||.|:|.||.|::..:||:|.||||||:.|..|||||||:.::||.
  Rat   240 ARVGPVSVSIDASLTSFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGN 304

  Fly   328 GGFMRILRNAGGFCGIASECSYP 350
            .|::.:.||....|||.:..|:|
  Rat   305 KGYVLLARNKNNACGITNLASFP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410	15/59 (25%)
		Peptidase_C1A	131..350	CDD:239068	94/219 (43%)
Ctsk	NP_113748.1	Inhibitor_I29	26..85	CDD:214853	15/58 (26%)
		Peptidase_C1	115..327	CDD:425470	94/220 (43%)