Protein Alignment CtsL2 and cpr-1

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_506002.2
• Gene: cpr-1 / 179637
• WormBaseID: WBGene00000781
• Length: 329
• Species: Caenorhabditis elegans
• Alignment Length: 330
• Identity: 83/330 - (25%)
• Similarity: 140/330 - (42%)
• Gaps: 60/330 - (18%)

  Fly    59 SIFAAKMSLITLSNKNADNGVSGFRL--GVNTLADMTRKEIATLLGS--KISEFGERYTNGHINF 119
            ::.|..::.:.:::::|...::|..|  .||:...:.:.|...:...  |......:|...|.:.
 Worm     8 ALCAVTLAFVPINHQSAVETLTGQALVDYVNSAQSLFKTEHVEITEEEMKFKLMDGKYAAAHSDE 72

  Fly   120 V--TARNPASANLPEMFD----WREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASL 178
            :  |.:....|::|..||    |.|...:.....|.. ||:||:|   ||.| .:..||.:....
 Worm    73 IRATEQEVVLASVPATFDSRTQWSECKSIKLIRDQAT-CGSCWAF---GAAE-MISDRTCIETKG 132

  Fly   179 SQQNLVD-------CADDYGNMGCDGGFQEYGFEYIRDHGVTLANKY------PY---TQTEMQC 227
            :||.::.       |....|| ||:||:......:....||.....|      ||   ..|...|
 Worm   133 AQQPIISPDDLLSCCGSSCGN-GCEGGYPIQALRWWDSKGVVTGGDYHGAGCKPYPIAPCTSGNC 196

  Fly   228 RQNETAGRPPRESLVKIRDYAT-------------ITPGDEEKMKEVIATLGPL--ACSMNADTI 277
            .:::|    |..|:.....|:|             ..|.:...::..|...||:  |.|:..|
 Worm   197 PESKT----PSCSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYED-- 255

  Fly   278 SFEQYSGGIYEDEECNQGEL--NHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGF 340
             |.:|..|:|:.   ..|:.  .|::.::|:|||:|..||::.||:..||||.||.:|.| ....
 Worm   256 -FYKYKSGVYKH---TAGKYLGGHAIKIIGWGTESGSPYWLVANSWGVNWGESGFFKIYR-GDDQ 315

  Fly   341 CGIAS 345
            |||.|
 Worm   316 CGIES 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410	6/39 (15%)
		Peptidase_C1A	131..350	CDD:239068	71/252 (28%)
cpr-1	NP_506002.2	Peptidase_C1A_CathepsinB	86..325	CDD:239111	71/252 (28%)