DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and cpr-4

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_504682.1	Gene:	cpr-4 / 179053	WormBaseID:	WBGene00000784	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	64/257 - (24%)
Similarity:	107/257 - (41%)	Gaps:	56/257 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 LPEMFDWREKGGVTPPGFQGVG-------CGACWSFATTGALEGH--LFRRTGVLASLSQQNLVD 185
            :|..||.|.:.    |....:.       ||:||:||...|....  :.....|...||.::::.
Worm    81 IPATFDARTQW----PNCMSINNIRDQSDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLS 141

  Fly   186 CADDYGNMGCDGGFQEYGFEYIRDHGVTLANKYPYTQTEMQCRQ------NETAGR--------- 235
            |..:.| .||:||:....::|:...|......|   :.:..|:.      .||.|.
Worm   142 CCSNCG-YGCEGGYPINAWKYLVKSGFCTGGSY---EAQFGCKPYSLAPCGETVGNVTWPSCPDD 202

  Fly   236 ----PPRESLVKIRDYATITPGDE----------EKMKEVIATL---GPLACSMNADTI--SFEQ 281
                |...:....::|......|:          :|:.::.|.:   ||:..   |.|:  .|.|
Worm   203 GYDTPACVNKCTNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEA---AFTVYEDFYQ 264

  Fly   282 YSGGIYEDEECNQGELNHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGI 343
            |..|:|. ....|....|::.::|:||:||..||::.||::.||||.|:.||:|.... |||
Worm   265 YKTGVYV-HTTGQELGGHAIRILGWGTDNGTPYWLVANSWNVNWGENGYFRIIRGTNE-CGI 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	64/256 (25%)
cpr-4	NP_504682.1	Peptidase_C1A_CathepsinB	82..331	CDD:239111	64/256 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161073
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750