DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and W07B8.4

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_503382.1	Gene:	W07B8.4 / 178611	WormBaseID:	WBGene00021072	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	272	Identity:	68/272 - (25%)
Similarity:	111/272 - (40%)	Gaps:	76/272 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 NLPEMFDWREKGGVTPPGFQGVG-------CGACWSFATTGALEGHLFRRTGVLAS------LSQ 180
            ::|:.:|.|:..    |....|.       ||:||:.|...|:..    ||.:.::      ||.
Worm    72 SIPDSYDVRDHW----PQCISVNNIRDQSHCGSCWAVAAAEAISD----RTCIASNGDVNTLLSA 128

  Fly   181 QNLVDCADDYGNM--GCDGGFQEYGFEYIRDHGVTLANKYPYTQTEMQCRQNETAGRPPRESL-- 241
            ::::.|.....|.  ||:||:....:.|...:|:.....:   :::..|:....|  |..|::
Worm   129 EDILTCCTGKFNCGDGCEGGYPIQAWRYWVKNGLVTGGSF---ESQYGCKPYSIA--PCGETIDG 188

  Fly   242 -------VKIRDYATI-----------TPGDEEK----------------MKEVIATLGPLACSM 272
                   :||.|....           .|.|::|                ..|::|. ||:....
Worm   189 VTWPECPMKISDTPKCEHHCTGNNSYPIPYDQDKHFGASAYAIGRSAKQIQTEILAH-GPVEVGF 252

  Fly   273 NADTISFEQ---YSGGIYEDEECNQGEL-NHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRI 333
                |.:|.   |..|||  .....||| .|:|.::|:|.:||..||:..||::..|||.|:.||
Worm   253 ----IVYEDFYLYKTGIY--THVAGGELGGHAVKMLGWGVDNGTPYWLAANSWNTVWGEKGYFRI 311

  Fly   334 LRNAGGFCGIAS 345
            ||.... |||.|
Worm   312 LRGVDE-CGIES 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	68/270 (25%)
W07B8.4	NP_503382.1	Peptidase_C1A_CathepsinB	74..327	CDD:239111	68/270 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820