DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and cpz-1

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_491023.2	Gene:	cpz-1 / 171829	WormBaseID:	WBGene00000788	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	77/239 - (32%)
Similarity:	121/239 - (50%)	Gaps:	39/239 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 SANLPEMFDWREKGGVT---------PPGFQGVGCGACWSFATTGALEGHL-FRRTGV--LASLS 179
            |.:||:.:|||:..|:.         .|.:    ||:||:|..|.||...: .:|...  .|.||
Worm    62 SEDLPKTWDWRDANGINYASADRNQHIPQY----CGSCWAFGATSALADRINIKRKNAWPQAYLS 122

  Fly   180 QQNLVDCADDYGNMGCDGGFQEYG-FEYIRDHGVTLANKYPYTQTEMQCRQNETAGRP-PRE--- 239
            .|.::||:   |...|..|.:..| ::|..:||:.......|...:.:|......|.. |.|
Worm   123 VQEVIDCS---GAGTCVMGGEPGGVYKYAHEHGIPHETCNNYQARDGKCDPYNRCGSCWPGECFS 184

  Fly   240 ----SLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHS 300
                :|.|:.:|.|:  ...||||..|...||:||.: |.|.:||.|:||||  :|....:::|.
Worm   185 IKNYTLYKVSEYGTV--HGYEKMKAEIYHKGPIACGI-AATKAFETYAGGIY--KEVTDEDIDHI 244

  Fly   301 VTVVGYGT--ENGRDYWIIKNSYSQNWGEGGFMRIL----RNAG 338
            ::|.|:|.  |:|.:|||.:||:.:.|||.|:.:|:    :|||
Worm   245 ISVHGWGVDHESGVEYWIGRNSWGEPWGEHGWFKIVTSQYKNAG 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	75/235 (32%)
cpz-1	NP_491023.2	Peptidase_C1A_CathepsinX	65..305	CDD:239149	76/236 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3812
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.700