Protein Alignment CG6347 and CTSW

DIOPT Version :9

• Sequence 1: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 91/365 - (24%)
• Similarity: 154/365 - (42%)
• Gaps: 67/365 - (18%)

  Fly    18 LGAVSLQQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKMSLITLSNKNADNGVSGF 82
            ||...|:..::| ||..:|....:|       |.||..:|..|||..::......:. |.|.:.|
Human    31 LGPQPLELKEAF-KLFQIQFNRSYL-------SPEEHAHRLDIFAHNLAQAQRLQEE-DLGTAEF 86

  Fly    83 RLGVNTLADMTRKEIATLLGSKISEFGERYTNGHI----NFVTARNPASANLPEMFDWREKGGVT 143
              ||...:|:|.:|...|       :|.|...|.:    ..:.:..| ..::|...|||:.....
Human    87 --GVTPFSDLTEEEFGQL-------YGYRRAAGGVPSMGREIRSEEP-EESVPFSCDWRKVASAI 141

  Fly   144 PPGFQGVGCGACWSFATTGALEGHLFRRT-GVLASLSQQNLVDCADDYGNM--GCDGGFQEYGF- 204
            .|......|..||:.|..|.:| .|:|.: .....:|.|.|:||    |..  ||.|||....|
Human   142 SPIKDQKNCNCCWAMAAAGNIE-TLWRISFWDFVDVSVQELLDC----GRCGDGCHGGFVWDAFI 201

  Fly   205 EYIRDHGVTLANKYPYTQTEMQCRQNETAGRPPR-ESLVKIRDYATITPGDEEKMKEVIATLGPL 268
            ..:.:.|:.....||:     |.:.......|.: :.:..|:|:..: ..:|.::.:.:||.||:
Human   202 TVLNNSGLASEKDYPF-----QGKVRAHRCHPKKYQKVAWIQDFIML-QNNEHRIAQYLATYGPI 260

  Fly   269 ACSMNADTISFEQYSGGIYE--DEECNQGELNHSVTVVGYGTENGRD------------------ 313
            ..::|...:  :.|..|:.:  ...|:...::|||.:||:|:....:
Human   261 TVTINMKPL--QLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHP 323

  Fly   314 --YWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYPI 351
              |||:|||:...|||.|:.|:.|.: ..|||.   .:|:
Human   324 TPYWILKNSWGAQWGEKGYFRLHRGS-NTCGIT---KFPL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	15/58 (26%)
		Peptidase_C1A	131..350	CDD:239068	62/245 (25%)
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	19/66 (29%)
		Peptidase_C1A	129..358	CDD:239068	62/245 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810