Protein Alignment CG6347 and CTSL

DIOPT Version :9

• Sequence 1: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001244900.1
• Gene: CTSL / 1514
• HGNCID: 2537
• Length: 333
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 116/318 - (36%)
• Similarity: 175/318 - (55%)
• Gaps: 38/318 - (11%)

  Fly    47 KVYSDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEFGER 111
            ::|...|..:|.:::...|.:|.|.|:....|...|.:.:|...|||.:|...::
Human    38 RLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVM---------- 92

  Fly   112 YTNGHINFVTARNPASANL---------PEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGH 167
              ||..|    |.|....:         |...||||||.|||...|| .||:||:|:.||||||.
Human    93 --NGFQN----RKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQG-QCGSCWAFSATGALEGQ 150

  Fly   168 LFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDH-GVTLANKYPYTQTEMQCRQNE 231
            :||:||.|.|||:||||||:...||.||:||..:|.|:|::|: |:.....|||..||..|:.|
Human   151 MFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYN- 214

  Fly   232 TAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGE 296
                 |:.|:.....:..| |..|:.:.:.:||:||::.:::|...||..|..|||.:.:|:..:
Human   215 -----PKYSVANDTGFVDI-PKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSED 273

  Fly   297 LNHSVTVVGYGTE----NGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYP 350
            ::|.|.|||||.|    :...||::|||:.:.||.||::::.::....|||||..|||
Human   274 MDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	13/49 (27%)
		Peptidase_C1A	131..350	CDD:239068	95/223 (43%)
CTSL	NP_001244900.1	Inhibitor_I29	29..87	CDD:214853	13/48 (27%)
		Peptidase_C1	114..332	CDD:395062	97/226 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149669
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.760