Protein Alignment CG6347 and CTSH

DIOPT Version :9

• Sequence 1: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_004381.2
• Gene: CTSH / 1512
• HGNCID: 2535
• Length: 335
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 125/356 - (35%)
• Similarity: 181/356 - (50%)
• Gaps: 38/356 - (10%)

  Fly     3 MCSTMWLQMTLGLALLGAVSL--QQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKM 65
            :|:..||   ||:.:.||..|  ..|:.|       :|..::.:..|.||.||..:|...||:..
Human     8 LCAGAWL---LGVPVCGAAELCVNSLEKF-------HFKSWMSKHRKTYSTEEYHHRLQTFASNW 62

  Fly    66 SLITLSNKNADNGVSGFRLGVNTLADMTRKEIA-TLLGSKISEFGERYTNGHINFVTARNPASAN 129
            ..|...|    ||...|::.:|..:||:..||. ..|.|:    .:..:....|::....|
Human    63 RKINAHN----NGNHTFKMALNQFSDMSFAEIKHKYLWSE----PQNCSATKSNYLRGTGP---- 115

  Fly   130 LPEMFDWREKGG-VTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNM 193
            .|...|||:||. |:|...|| .||:||:|:||||||..:...||.:.||::|.|||||.|:.|.
Human   116 YPPSVDWRKKGNFVSPVKNQG-ACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179

  Fly   194 GCDGGFQEYGFEYI-RDHGVTLANKYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEK 257
            ||.||.....|||| .:.|:...:.|||...:..|:..      |.:::..::|.|.||..|||.
Human   180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ------PGKAIGFVKDVANITIYDEEA 238

  Fly   258 MKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQ--GELNHSVTVVGYGTENGRDYWIIKNS 320
            |.|.:|...|::.:... |..|..|..|||....|::  .::||:|..||||.:||..|||:|||
Human   239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302

  Fly   321 YSQNWGEGGFMRILRNAGGFCGIASECSYPI 351
            :...||..|:..|.|.. ..||:|:..||||
Human   303 WGPQWGMNGYFLIERGK-NMCGLAACASYPI 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	17/58 (29%)
		Peptidase_C1A	131..350	CDD:239068	89/222 (40%)
CTSH	NP_004381.2	Inhibitor_I29	35..90	CDD:285458	17/58 (29%)
		Peptidase_C1	117..332	CDD:278538	90/223 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830