Protein Alignment CtsL2 and Ctsw

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_034115.2
• Gene: Ctsw / 13041
• MGIID: 1338045
• Length: 371
• Species: Mus musculus
• Alignment Length: 386
• Identity: 101/386 - (26%)
• Similarity: 165/386 - (42%)
• Gaps: 71/386 - (18%)

  Fly     3 MCSTMWLQMTLGLALLG---AVSLQQLQSFPKLCDVQN-FDDF-LRQTGKVYSDEERVYRESIFA 62
            |..|..|...|.|.|.|   :.||....:.|:..:::. |..| :|.....::..|...|.||||
Mouse     1 MTLTAHLSYFLVLLLAGQGLSDSLLTKDAGPRPLELKEVFKLFQIRFNRSYWNPAEYTRRLSIFA 65

  Fly    63 AKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEFGERYTNGHINFVTAR---N 124
            ..::......:. |.|.:.|  |....:|:|.:|...|.|.:.|.  ||..|     :|.:   |
Mouse    66 HNLAQAQRLQQE-DLGTAEF--GETPFSDLTEEEFGQLYGQERSP--ERTPN-----MTKKVESN 120

  Fly   125 PASANLPEMFDWRE-KGGVTPPGFQGVGCGACWSFATTGALEGHLFR-RTGVLASLSQQNLVDCA 187
            ....::|...|||: |..::....|| .|..||:.|....::. |:| :......:|.|.|:||
Mouse   121 TWGESVPRTCDWRKAKNIISSVKNQG-SCKCCWAMAAADNIQA-LWRIKHQQFVDVSVQELLDC- 182

  Fly   188 DDYGNMGCDGGF--QEYGFEYIRDHGVTLANKYPYTQTEMQCRQNETAGRPPRESLVK------- 243
            :..|| ||:|||  ..| ...:.:.|:.....||:           ...|.|...|.|
Mouse   183 ERCGN-GCNGGFVWDAY-LTVLNNSGLASEKDYPF-----------QGDRKPHRCLAKKYKKVAW 234

  Fly   244 IRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYE--DEECNQGELNHSVTVVGY 306
            |:|: |:...:|:.:...:|..||:..::|...:  :.|..|:.:  ...|:..:::|||.:||:
Mouse   235 IQDF-TMLSNNEQAIAHYLAVHGPITVTINMKLL--QHYQKGVIKATPSSCDPRQVDHSVLLVGF 296

  Fly   307 GTE-----------------NGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYP 350
            |.|                 :...|||:|||:..:|||.|:.|:.| ....||:.   .||
Mouse   297 GKEKEGMQTGTVLSHSRKRRHSSPYWILKNSWGAHWGEKGYFRLYR-GNNTCGVT---KYP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410	15/59 (25%)
		Peptidase_C1A	131..350	CDD:239068	65/248 (26%)
Ctsw	NP_034115.2	Inhibitor_I29	40..96	CDD:214853	15/58 (26%)
		Peptidase_C1A	127..356	CDD:239068	67/250 (27%)