Protein Alignment CtsL2 and Ctsc

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_034112.3
• Gene: Ctsc / 13032
• MGIID: 109553
• Length: 462
• Species: Mus musculus
• Alignment Length: 318
• Identity: 102/318 - (32%)
• Similarity: 133/318 - (41%)
• Gaps: 89/318 - (27%)

  Fly    98 ATLLGSKISEFGER-YTNGHINFVTARN------------------------------------P 125
            |..||.....:.|| ||:.| |||.|.|                                    |
Mouse   153 AAHLGGLQERYSERLYTHNH-NFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPKP 216

  Fly   126 AS---------ANLPEMFDWREKGGV--TPPGFQGVGCGACWSFATTGALEGHLFRRTGVLAS-- 177
            |.         .||||.:|||...||  ..|......||:|:|||:.|.||.    |..:|.:
Mouse   217 APMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEA----RIRILTNNS 277

  Fly   178 ----LSQQNLVDCADDYGNMGCDGGFQE-YGFEYIRDHGVTLANKYPYTQTEMQCRQNETAGRPP 237
                ||.|.:|.|: .|. .||||||.. ...:|.:|.||...:.:|||..:..|:        |
Mouse   278 QTPILSPQEVVSCS-PYA-QGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCK--------P 332

  Fly   238 RESLVKI--RDYATITPG------DEEKMKEVIATLGPLACSMNADTISFEQYSGGIYE----DE 290
            ||:.::.  .||..:  |      :|..||..:...||:|.:..... .|..|..|||.    .:
Mouse   333 RENCLRYYSSDYYYV--GGFYGGCNEALMKLELVKHGPMAVAFEVHD-DFLHYHSGIYHHTGLSD 394

  Fly   291 ECNQGEL-NHSVTVVGYGTE--NGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIAS 345
            ..|..|| ||:|.:||||.:  .|.:|||||||:..||||.|:.||.|.... |.|.|
Mouse   395 PFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDE-CAIES 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410
		Peptidase_C1A	131..350	CDD:239068	85/239 (36%)
Ctsc	NP_034112.3	CathepsinC_exc	25..138	CDD:462598
		Pox_I6	168..>204	CDD:333259	8/36 (22%)
		Peptidase_C1A_CathepsinC	230..459	CDD:239112	86/240 (36%)