Protein Alignment CG6347 and Ctsb

DIOPT Version :9

• Sequence 1: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_031824.1
• Gene: Ctsb / 13030
• MGIID: 88561
• Length: 339
• Species: Mus musculus
• Alignment Length: 385
• Identity: 94/385 - (24%)
• Similarity: 140/385 - (36%)
• Gaps: 106/385 - (27%)

  Fly     7 MWLQMTLGLALLGAVSLQQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKMSLITLS 71
            ||..:.|...||...|.....||..|.|                               .||...
Mouse     1 MWWSLILLSCLLALTSAHDKPSFHPLSD-------------------------------DLINYI 34

  Fly    72 NKNADNGVSGFRLGVNTLADMTRKEIATLLGS-KIS---EFGERYTNGHINFVTARNPASANLPE 132
            ||......:| |...|......:|...|:||. |:.   .|||                ..:|||
Mouse    35 NKQNTTWQAG-RNFYNVDISYLKKLCGTVLGGPKLPGRVAFGE----------------DIDLPE 82

  Fly   133 MFDWREK-------GGVTPPGFQGVGCGACWSFATTGALEGHLFRRTG--VLASLSQQNLVDCAD 188
            .||.||:       |.:...|    .||:||:|....|:.......|.  |...:|.::|:.|..
Mouse    83 TFDAREQWSNCPTIGQIRDQG----SCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCG 143

  Fly   189 DYGNMGCDGGFQEYGFEYIRDHGVTLANKY-------PYTQTEMQCRQNETAGRPP--------- 237
            .....||:||:....:.:....|:.....|       |||..  .|..:....|||
Mouse   144 IQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIP--PCEHHVNGSRPPCTGEGDTPR 206

  Fly   238 ---------RESLVKIRDYATITPGDEEKMKEVIATL---GPLACSMNADTI--SFEQYSGGIYE 288
                     ..|..:.:.:...:......:||::|.:   ||:.   .|.|:  .|..|..|:|:
Mouse   207 CNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVE---GAFTVFSDFLTYKSGVYK 268

  Fly   289 DEECNQGEL--NHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASE 346
            .|   .|::  .|::.::|:|.|||..||:..||::.:||:.||.:|||.. ..|||.||
Mouse   269 HE---AGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGE-NHCGIESE 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	8/58 (14%)
		Peptidase_C1A	131..350	CDD:239068	68/257 (26%)
Ctsb	NP_031824.1	Propeptide_C1	26..65	CDD:285358	12/70 (17%)
		Peptidase_C1A_CathepsinB	81..328	CDD:239111	68/257 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820