DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and ctsz

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001106427.1	Gene:	ctsz / 100127597	XenbaseID:	XB-GENE-959211	Length:	296	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	134/253 - (52%)	Gaps:	36/253 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 ANLPEMFDWREKGG---VTPPGFQGVG--CGACWSFATTGALEGHL-FRRTGVLAS--LSQQNLV 184
            :.||:::|||...|   |:....|.:.  ||:||:..:|.|:...: .:|.||..|  ||.|:::
Frog    51 SELPKVWDWRNLNGTNYVSTTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGVWPSAYLSVQHVI 115

  Fly   185 DCADDYGNMG-CDGGFQEYGFEYIRDHGV--TLANKYPYTQTEM----QCRQNETAGR---PPRE 239
            |||    |.| |:||.....:||...||:  ...|.|.....:.    ||....|.|:   ....
Frog   116 DCA----NAGSCEGGDHGGVWEYANSHGIPDETCNNYQARDQKCDKFNQCGTCVTFGKCFYLSNY 176

  Fly   240 SLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVV 304
            :|.|:.|:.::: |.|:.|.|:... ||::|.:.| |...:.|:||:|.:.: ....:||.|:|.
Frog   177 TLWKVGDFGSVS-GREKMMAEIYKN-GPISCGIMA-TEKLDAYTGGLYAEYQ-PSAMINHIVSVA 237

  Fly   305 GYG-TENGRDYWIIKNSYSQNWGEGGFMRILRNA--GG-----FCGIASECSY--PIL 352
            |:| .|:|.:|||::||:.:.|||.|::||:.:|  ||     ...|..:|:|  |||
Frog   238 GWGLDESGAEYWIVRNSWGEPWGERGWLRIVTSAYKGGKGADYNLAIEEDCAYGDPIL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	79/246 (32%)
ctsz	NP_001106427.1	Peptidase_C1A_CathepsinX	53..294	CDD:239149	80/248 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010