DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6337 and cpr-1

DIOPT Version :9

Sequence 1:	NP_001286395.1	Gene:	CG6337 / 36530	FlyBaseID:	FBgn0033873	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_506002.2	Gene:	cpr-1 / 179637	WormBaseID:	WBGene00000781	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	89/375 - (23%)
Similarity:	132/375 - (35%)	Gaps:	107/375 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LCCLLLTIDSGWAF---NH--------GQDLVDFQTYEDNFNKT-YASTSARNFANYYFIYNRNQ 58
            ||.:.|      ||   ||        ||.|||:.....:..|| :...:.....  :.:.:...
Worm     9 LCAVTL------AFVPINHQSAVETLTGQALVDYVNSAQSLFKTEHVEITEEEMK--FKLMDGKY 65

  Fly    59 VAQHNAQADRNRTTYREAVNQFSDIRLIQFAALLPKAVNTVTSAASDPPASQAASASFDIITDFG 123
            .|.|   :|..|.|.:|.|                        .||.|       |:||..|.:.
Worm    66 AAAH---SDEIRATEQEVV------------------------LASVP-------ATFDSRTQWS 96

  Fly   124 LTVAVE---DQGVNCSSSWAYATAKAVEIMNAVQTANPLPSSLSAQQLLDCAG--MGTGCSTQTP 183
            ...:::   || ..|.|.||:..|:.:.....::|.......:|...||.|.|  .|.||....|
Worm    97 ECKSIKLIRDQ-ATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLLSCCGSSCGNGCEGGYP 160

  Fly   184 LAALNYLTQ---LTDAYLYPEVDY------PNNNSLKTPGMCQPPSSVSVGVKL-AGYSTVADND 238
            :.||.:...   :|..      ||      |...:..|.|.|....:.|..:.. :||||....|
Worm   161 IQALRWWDSKGVVTGG------DYHGAGCKPYPIAPCTSGNCPESKTPSCSMSCQSGYSTAYAKD 219

  Fly   239 D-------------AAVMRYVSNGFPVIVEYNPATFG----FMQYSSGVYVQETRALTNPK--SS 284
            .             |::...:....||     .|.|.    |.:|.||||..     |..|  ..
Worm   220 KHFGVSAYAVPKNAASIQAEIYANGPV-----EAAFSVYEDFYKYKSGVYKH-----TAGKYLGG 274

  Fly   285 QFLVVVGYDHDVDSNLDYWRCLNSFGDTWGEEGYIRIVRRSNQPIAKNAV 334
            ..:.::|:  ..:|...||...||:|..|||.|:.:|.|..:|...::||
Worm   275 HAIKIIGW--GTESGSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAV 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	9/60 (15%)
CG6337	NP_001286395.1	Peptidase_C1A	114..336	CDD:239068	65/255 (25%)
cpr-1	NP_506002.2	Peptidase_C1A_CathepsinB	86..325	CDD:239111	66/263 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810