DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6337 and cpz-1

DIOPT Version :9

Sequence 1:	NP_001286395.1	Gene:	CG6337 / 36530	FlyBaseID:	FBgn0033873	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_491023.2	Gene:	cpz-1 / 171829	WormBaseID:	WBGene00000788	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	55/220 - (25%)
Similarity:	91/220 - (41%)	Gaps:	35/220 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 GLTVAVEDQGVN----CSSSWAYATAKAVEIMNAVQTANPLPSS-LSAQQLLDCAGMGTGCSTQT 182
            |:..|..|:..:    |.|.||:....|:.....::..|..|.: ||.|:::||:|.||......
Worm    76 GINYASADRNQHIPQYCGSCWAFGATSALADRINIKRKNAWPQAYLSVQEVIDCSGAGTCVMGGE 140

  Fly   183 PLAALNYLTQLTDAYLYPEV---DYPNNNSLKTP----GMCQPPSSVSVG----VKLAGYSTVAD 236
            |.....|..:    :..|..   :|...:....|    |.|.|....|:.    .|::.|.||..
Worm   141 PGGVYKYAHE----HGIPHETCNNYQARDGKCDPYNRCGSCWPGECFSIKNYTLYKVSEYGTVHG 201

  Fly   237 NDDAAVMRY----VSNGFPVIVEYNPATFGFMQYSSGVYVQETRALTNPKSSQFLVVVGYDHDVD 297
            .:......|    ::.|.       .||..|..|:.|:|    :.:|:......:.|.|:..|.:
Worm   202 YEKMKAEIYHKGPIACGI-------AATKAFETYAGGIY----KEVTDEDIDHIISVHGWGVDHE 255

  Fly   298 SNLDYWRCLNSFGDTWGEEGYIRIV 322
            |.::||...||:|:.|||.|:.:||
Worm   256 SGVEYWIGRNSWGEPWGEHGWFKIV 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458
CG6337	NP_001286395.1	Peptidase_C1A	114..336	CDD:239068	55/220 (25%)
cpz-1	NP_491023.2	Peptidase_C1A_CathepsinX	65..305	CDD:239149	55/220 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820