Protein Alignment CG6337 and CTSW

DIOPT Version :9

• Sequence 1: NP_001286395.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 90/381 - (23%)
• Similarity: 141/381 - (37%)
• Gaps: 101/381 - (26%)

  Fly     8 CLLLTIDSGWAFN-----HGQDL--------VDFQTYEDNFNKTYASTSARNFANYYFIYNRNQV 59
            |||..:.:|.|..     ..|||        ..|:.::..||::|.|....        .:|..:
Human     9 CLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEH--------AHRLDI 65

  Fly    60 AQHN-AQADR----NRTTYREAVNQFSDIRLIQFAAL--LPKAVNTVTS-----AASDPPASQAA 112
            ..|| |||.|    :..|....|..|||:...:|..|  ..:|...|.|     .:.:|..|...
Human    66 FAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPF 130

  Fly   113 SASFDIITDFGLTVAVEDQGVNCSSSWAYATAKAVEIMNAVQTANPLPSSLSAQQLLDCAGMGTG 177
            |..:..:.  .....::|| .||:..||.|.|..:|.:..:...:.:  .:|.|:||||...|.|
Human   131 SCDWRKVA--SAISPIKDQ-KNCNCCWAMAAAGNIETLWRISFWDFV--DVSVQELLDCGRCGDG 190

  Fly   178 CSTQTPLAALNYLTQLTDAYLYPEVDYPNNNSLKTPGMCQPPSSVSVGVKLAGYSTVA------- 235
            |.......|  ::|.|.::.|..|.|||....::. ..|.|..          |..||
Human   191 CHGGFVWDA--FITVLNNSGLASEKDYPFQGKVRA-HRCHPKK----------YQKVAWIQDFIM 242

  Fly   236 -DNDDAAVMRYVSNGFPVIVEYN---------------PAT--------------FGFMQYSSGV 270
             .|::..:.:|::...|:.|..|               |.|              ||.::...|:
Human   243 LQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGI 307

  Fly   271 YVQETRALTNPKSSQFLVVVGYDHDVDSNLDYWRCLNSFGDTWGEEGYIRIVRRSN 326
            :.:...:.:.|:.         .|..    .||...||:|..|||:||.|:.|.||
Human   308 WAETVSSQSQPQP---------PHPT----PYWILKNSWGAQWGEKGYFRLHRGSN 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	17/64 (27%)
		Peptidase_C1A	114..336	CDD:239068	57/250 (23%)
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	17/63 (27%)
		Peptidase_C1A	129..358	CDD:239068	58/253 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900