Protein Alignment CG6337 and CTSS

DIOPT Version :9

• Sequence 1: NP_001286395.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_004070.3
• Gene: CTSS / 1520
• HGNCID: 2545
• Length: 331
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 88/351 - (25%)
• Similarity: 139/351 - (39%)
• Gaps: 46/351 - (13%)

  Fly     6 LCCLLLTIDSGWAFNHGQDLVD--FQTYEDNFNKTYASTSARNFANYYFIYNRNQVAQHNAQADR 68
            |.|:||...|..|..|....:|  :..::..:.|.|...:........:..|...|..||.:...
Human     4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSM 68

  Fly    69 NRTTYREAVNQFSDIRLIQFAALL-----PKAVNTVTSAASDPPASQAASASFDIITDFGLTVAV 128
            ...:|...:|...|:...:..:|:     |.......:..|:|......|..:   .:.|....|
Human    69 GMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDW---REKGCVTEV 130

  Fly   129 EDQGVNCSSSWAYATAKAVEIMNAVQTANPLPSSLSAQQLLDCAGM---GTGCSTQTPLAALNYL 190
            :.|| :|.:.||::...|:|....::|...:  |||||.|:||:..   ..||:......|..|:
Human   131 KYQG-SCGACWAFSAVGALEAQLKLKTGKLV--SLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYI 192

  Fly   191 TQL----TDA-YLYPEVDYPNNNSLKTPGMCQPPSSVSVGVKLAGYSTVADNDDAAVMRYVSNGF 250
            ...    :|| |.|..:|.          .||..|...... .:.|:.:....:..:...|:|..
Human   193 IDNKGIDSDASYPYKAMDQ----------KCQYDSKYRAAT-CSKYTELPYGREDVLKEAVANKG 246

  Fly   251 PVIVEYNPATFGFMQYSSGVYVQETRALTNPKSSQ----FLVVVGYDHDVDSNLDYWRCLNSFGD 311
            ||.|..:.....|..|.||||.:       |..:|    .::||||. |::.. :||...||:|.
Human   247 PVSVGVDARHPSFFLYRSGVYYE-------PSCTQNVNHGVLVVGYG-DLNGK-EYWLVKNSWGH 302

  Fly   312 TWGEEGYIRIVRRSNQPIAKNAVFPS 337
            .:|||||||:.|....... .|.|||
Human   303 NFGEEGYIRMARNKGNHCG-IASFPS 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	9/59 (15%)
		Peptidase_C1A	114..336	CDD:239068	63/233 (27%)
CTSS	NP_004070.3	PTZ00203	5..326	CDD:185513	84/347 (24%)
		Inhibitor_I29	28..87	CDD:214853	9/58 (16%)
		Peptidase_C1	115..329	CDD:278538	67/240 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910