Protein Alignment CG6337 and CTSO

DIOPT Version :9

• Sequence 1: NP_001286395.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001325.1
• Gene: CTSO / 1519
• HGNCID: 2542
• Length: 321
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 134/312 - (42%)
• Gaps: 52/312 - (16%)

  Fly    35 FNKTYASTSARNFANYYFIYNRNQVAQHNAQADRNRTTYREAVNQFSDIRLIQFAALLPKAVNTV 99
            |..|:..:..|..|.:....||::.......::.:...|  .:||||.:...:|     ||:...
Human    29 FTPTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAFY--GINQFSYLFPEEF-----KAIYLR 86

  Fly   100 TSAASDPPASQAASASFDIIT--------DFGLTVAVEDQGVNCSSSWAYATAKAVEIMNAVQTA 156
            :..:..|..|.....|...::        |..:...|.:|.: |...||::...|||...|:: .
Human    87 SKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQM-CGGCWAFSVVGAVESAYAIK-G 149

  Fly   157 NPLPSSLSAQQLLDCAGMGTGCSTQTPLAALNYLTQLTDAYLYPEVDYP---NNNSLKTPGMCQP 218
            .|| ..||.||::||:....||:..:.|.|||:|.:: ...|..:.:||   .|      |:|..
Human   150 KPL-EDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKM-QVKLVKDSEYPFKAQN------GLCHY 206

  Fly   219 PSSVSVGVKLAGYST--VADNDDAAVMRYVSNGFPVIVEYNPATF-----GFMQY--SSGVYVQE 274
            .|....|..:.|||.  .:|.:|......::.| |::|..:..::     |.:|:  |||
Human   207 FSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFG-PLVVIVDAVSWQDYLGGIIQHHCSSG----- 265

  Fly   275 TRALTNPKSSQFLVVVGYDHDVDSNLDYWRCLNSFGDTWGEEGYIRIVRRSN 326
                   :::..:::.|:|.  ..:..||...||:|.:||.:||..:...||
Human   266 -------EANHAVLITGFDK--TGSTPYWIVRNSWGSSWGVDGYAHVKMGSN 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	11/52 (21%)
		Peptidase_C1A	114..336	CDD:239068	60/233 (26%)
CTSO	NP_001325.1	Peptidase_C1A	109..319	CDD:239068	59/225 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12411
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010