Protein Alignment CG6337 and CTSK

DIOPT Version :10

• Sequence 1: NP_610905.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_000387.1
• Gene: CTSK / 1513
• HGNCID: 2536
• Length: 329
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 83/330 - (25%)
• Similarity: 130/330 - (39%)
• Gaps: 55/330 - (16%)

  Fly    29 QTYEDNFNKTYASTSARNFANYYFIYNRN--QVAQHNAQADRNRTTYREAVNQFSDIRLIQFAAL 91
            :|:...:|......|.|      .|:.:|  .::.||.:|.....||..|:|...|:       .
Human    31 KTHRKQYNNKVDEISRR------LIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM-------T 82

  Fly    92 LPKAVNTVTSAASDPPASQAASASFDIITDF-------------GLTVAVEDQGVNCSSSWAYAT 143
            ..:.|..:|..  ..|.|.:.|.....|.::             |....|::|| .|.|.||:::
Human    83 SEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG-QCGSCWAFSS 144

  Fly   144 AKAVEIMNAVQTANPLPSSLSAQQLLDCAGMGTGCSTQTPLAALNYLTQ-----LTDAYLYPEVD 203
            ..|:|.....:|...|  :||.|.|:||.....||.......|..|:.:     ..|||.|.
Human   145 VGALEGQLKKKTGKLL--NLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYV--- 204

  Fly   204 YPNNNSLKTPGMCQPPSSVSVGVKLAGYSTVADNDDAAVMRYVSNGFPVIVEYNPATFGFMQYSS 268
                 ..:...|..|....:   |..||..:.:.::.|:.|.|:...||.|..:.:...|..||.
Human   205 -----GQEESCMYNPTGKAA---KCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSK 261

  Fly   269 GVYVQETRALTNPKSSQFLVVVGYDHDVDSNLDYWRCLNSFGDTWGEEGYIRIVRRSNQP--IAK 331
            |||..|  :..:...:..::.|||  .:.....:|...||:|:.||.:|||.:.|..|..  ||.
Human   262 GVYYDE--SCNSDNLNHAVLAVGY--GIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN 322

  Fly   332 NAVFP 336
            .|.||
Human   323 LASFP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_610905.1	Inhibitor_I29	28..82	CDD:214853	13/54 (24%)
		Peptidase_C1A	114..336	CDD:239068	62/241 (26%)
CTSK	NP_000387.1	Inhibitor_I29	26..85	CDD:214853	14/66 (21%)
		Peptidase_C1	115..327	CDD:425470	61/229 (27%)