Protein Alignment CG6337 and CTSH

DIOPT Version :9

• Sequence 1: NP_001286395.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_004381.2
• Gene: CTSH / 1512
• HGNCID: 2535
• Length: 335
• Species: Homo sapiens
• Alignment Length: 334
• Identity: 93/334 - (27%)
• Similarity: 136/334 - (40%)
• Gaps: 56/334 - (16%)

  Fly    28 FQTYEDNFNKTYASTSARNFANYYFIYNRNQVAQHNAQADRNRTTYREAVNQFSDIRLIQFAALL 92
            |:::.....||| ||...:.....|..|..::..||    ....|::.|:|||||   :.||.:.
Human    35 FKSWMSKHRKTY-STEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSD---MSFAEIK 91

  Fly    93 PKAV------------NTVTSAASDPPASQAASASFDIITDFGLTVAVEDQGVNCSSSWAYATAK 145
            .|.:            |.:......||       |.|..........|::||. |.|.|.::|..
Human    92 HKYLWSEPQNCSATKSNYLRGTGPYPP-------SVDWRKKGNFVSPVKNQGA-CGSCWTFSTTG 148

  Fly   146 AVEIMNAVQTANPLPSSLSAQQLLDCAG--MGTGCSTQTPLAALNYLTQLTDAYLYPEVDYPNNN 208
            |:|...|:.|...|  ||:.|||:|||.  ...||....|..|..|:  |.:..:..|..||...
Human   149 ALESAIAIATGKML--SLAEQQLVDCAQDFNNHGCQGGLPSQAFEYI--LYNKGIMGEDTYPYQG 209

  Fly   209 SLKTPGMCQPPSSVSVG-VKLAGYSTVADNDDAAVMRYVSNGFPVIVEYNPATFG------FMQY 266
            .   .|.|:.....::| ||.....|:.| ::|.|        ..:..|||.:|.      ||.|
Human   210 K---DGYCKFQPGKAIGFVKDVANITIYD-EEAMV--------EAVALYNPVSFAFEVTQDFMMY 262

  Fly   267 SSGVYVQETRALTNPKSSQFLVVVGYDHDVDSNLDYWRCLNSFGDTWGEEGYIRIVRRSNQ-PIA 330
            .:|:|...:...|..|.:..::.|||..  .:.:.||...||:|..||..||..|.|..|. .:|
Human   263 RTGIYSSTSCHKTPDKVNHAVLAVGYGE--KNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLA 325

  Fly   331 KNAVFPSAL 339
            ..|.:|..|
Human   326 ACASYPIPL 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	17/59 (29%)
		Peptidase_C1A	114..336	CDD:239068	68/231 (29%)
CTSH	NP_004381.2	Inhibitor_I29	35..90	CDD:285458	19/62 (31%)
		Peptidase_C1	117..332	CDD:278538	70/240 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820