Protein Alignment CG6337 and Ctsc

DIOPT Version :10

• Sequence 1: NP_610905.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_034112.3
• Gene: Ctsc / 13032
• MGIID: 109553
• Length: 462
• Species: Mus musculus
• Alignment Length: 353
• Identity: 80/353 - (22%)
• Similarity: 132/353 - (37%)
• Gaps: 85/353 - (24%)

  Fly    45 RNFANYYFIYNRNQVAQHNAQADRNRTTYREAVNQFSDIRLIQFAALLPKAVNTVTSAASDPPAS 109
            ||:|    .:...:|..|..:.:.|.........::|: ||........||:|||..:.:.....
Mouse   132 RNWA----CFVGKKVESHIEKVNMNAAHLGGLQERYSE-RLYTHNHNFVKAINTVQKSWTATAYK 191

  Fly   110 QAASASF-DIITDFG------------LTVAVED--------------QGVN----------CSS 137
            :....|. |:|...|            :|..::.              ||||          |.|
Mouse   192 EYEKMSLRDLIRRSGHSQRIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGS 256

  Fly   138 SWAYATAKAVEIMNAVQTANPLPSSLSAQQLLDCAGMGTGCSTQTP-LAALNYLTQL----TDAY 197
            .:::|:...:|....:.|.|.....||.|:::.|:....||....| |.|..|....    ...:
Mouse   257 CYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEESCF 321

  Fly   198 LYPEVDYPNNNSLKTPGMCQPPSSVSVGVKLAGYSTVAD-----------NDDAAVMRYVSNGFP 251
            .|...|.|          |:|..:.     |..||  :|           |:....:..|.:| |
Mouse   322 PYTAKDSP----------CKPRENC-----LRYYS--SDYYYVGGFYGGCNEALMKLELVKHG-P 368

  Fly   252 VIVEYNPATFGFMQYSSGVYVQETRALTNP-----KSSQFLVVVGYDHDVDSNLDYWRCLNSFGD 311
            :.|.:. ....|:.|.||:|  ....|::|     .::..:::|||..|..:.::||...||:|.
Mouse   369 MAVAFE-VHDDFLHYHSGIY--HHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWGS 430

  Fly   312 TWGEEGYIRIVRRSNQPIAKNAVFPSAL 339
            .|||.||.|| ||.....|..::..:|:
Mouse   431 NWGESGYFRI-RRGTDECAIESIAVAAI 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_610905.1	Inhibitor_I29	28..82	CDD:214853	6/36 (17%)
		Peptidase_C1A	114..336	CDD:239068	65/279 (23%)
Ctsc	NP_034112.3	CathepsinC_exc	25..138	CDD:462598	3/9 (33%)
		Pox_I6	168..>204	CDD:333259	8/35 (23%)
		Peptidase_C1A_CathepsinC	230..459	CDD:239112	61/250 (24%)