Protein Alignment CG6337 and CTSC

DIOPT Version :9

• Sequence 1: NP_001286395.1
• Gene: CG6337 / 36530
• FlyBaseID: FBgn0033873
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001805.4
• Gene: CTSC / 1075
• HGNCID: 2528
• Length: 463
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 80/337 - (23%)
• Similarity: 126/337 - (37%)
• Gaps: 49/337 - (14%)

  Fly    17 WAFNHGQDLVDFQTYEDN--FNKTYASTSARNFANYYFIYNRNQVAQHNA-QADRNRTTYREAVN 78
            ||...|:.:   .|..:|  .|..:...|...::|..:.|:.|.|...|| |.....|||.|
Human   134 WACFTGKKV---GTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYME--- 192

  Fly    79 QFSDIRLIQFAALLPKAVNTVTSAASDPPASQAAS---------ASFDIITDFGLTVA--VEDQG 132
                ...:....::.::...........||...|.         .|:|.....|:...  |.:|
Human   193 ----YETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQ- 252

  Fly   133 VNCSSSWAYATAKAVEIMNAVQTANPLPSSLSAQQLLDCAGMGTGCSTQTPLAALNYLTQLTDAY 197
            .:|.|.:::|:...:|....:.|.|.....||.|:::.|:....||....|........|  |..
Human   253 ASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQ--DFG 315

  Fly   198 LYPEVDYPNNNSLKTPGMCQPPSSV---------SVGVKLAGYSTVADNDDAAVMRYVSNGFPVI 253
            |..|..:|...   |...|:.....         .||....|.     |:....:..|.:| |:.
Human   316 LVEEACFPYTG---TDSPCKMKEDCFRYYSSEYHYVGGFYGGC-----NEALMKLELVHHG-PMA 371

  Fly   254 VEYNPATFGFMQYSSGVYVQE-TRALTNP--KSSQFLVVVGYDHDVDSNLDYWRCLNSFGDTWGE 315
            |.:. ....|:.|..|:|... .|...||  .::..:::|||..|..|.:|||...||:|..|||
Human   372 VAFE-VYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGE 435

  Fly   316 EGYIRIVRRSNQ 327
            .||.||.|.:::
Human   436 NGYFRIRRGTDE 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458	15/62 (24%)
		Peptidase_C1A	114..336	CDD:239068	59/228 (26%)
CTSC	NP_001805.4	CathepsinC_exc	26..138	CDD:312344	2/3 (67%)
		Peptidase_C1A_CathepsinC	231..460	CDD:239112	59/230 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820