DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6337 and ctsz

DIOPT Version :9

Sequence 1:	NP_001286395.1	Gene:	CG6337 / 36530	FlyBaseID:	FBgn0033873	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001106427.1	Gene:	ctsz / 100127597	XenbaseID:	XB-GENE-959211	Length:	296	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	55/213 - (25%)
Similarity:	89/213 - (41%)	Gaps:	49/213 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 CSSSWAYATAKAVEIMNAVQTANPLPSS-LSAQQLLDCAGMGT----------------GCSTQT 182
            |.|.||:.:..|:.....::.....||: ||.|.::|||..|:                |...:|
Frog    80 CGSCWAHGSTSAMADRINIKRKGVWPSAYLSVQHVIDCANAGSCEGGDHGGVWEYANSHGIPDET 144

  Fly   183 PLAALNYLTQLTDAYLYPEVDYPNN-NSLKTPGMCQPPSSVSVGVKLAGYSTVADNDDAAVMRYV 246
               ..||  |..|    .:.|..|. .:..|.|.|...|:.::. |:..:.:|:..:......|
Frog   145 ---CNNY--QARD----QKCDKFNQCGTCVTFGKCFYLSNYTLW-KVGDFGSVSGREKMMAEIY- 198

  Fly   247 SNGFPVIVEYNPATFGFM------QYSSGVYVQ-ETRALTNPKSSQFLVVVGYDHDVDSNLDYWR 304
            .||        |.:.|.|      .|:.|:|.: :..|:.|    ..:.|.|:..| :|..:||.
Frog   199 KNG--------PISCGIMATEKLDAYTGGLYAEYQPSAMIN----HIVSVAGWGLD-ESGAEYWI 250

  Fly   305 CLNSFGDTWGEEGYIRIV 322
            ..||:|:.|||.|::|||
Frog   251 VRNSWGEPWGERGWLRIV 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6337	NP_001286395.1	Inhibitor_I29	28..88	CDD:285458
CG6337	NP_001286395.1	Peptidase_C1A	114..336	CDD:239068	55/213 (26%)
ctsz	NP_001106427.1	Peptidase_C1A_CathepsinX	53..294	CDD:239149	55/213 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010