DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17716 and bcam

DIOPT Version :9

Sequence 1:	NP_001286391.1	Gene:	CG17716 / 36521	FlyBaseID:	FBgn0000633	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_001352817.1	Gene:	bcam / 767689	ZFINID:	ZDB-GENE-060929-620	Length:	611	Species:	Danio rerio

Alignment Length:	468	Identity:	114/468 - (24%)
Similarity:	194/468 - (41%)	Gaps:	123/468 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 TDYRFIKEANGALTITNVMLEDDGKWQCE--------AENTRRYTENARPVKLVVLDRPKPPYLL 342
            || |:..|.:.:|.|:.|.::|..|:.|:        ||:.......:.|.|.:|:  |.|..:.
Zfish    87 TD-RYTIEKDMSLNISQVTVDDHKKFICQVTAGPVGTAESATEVKVFSAPEKPMVV--PNPQKIF 148

  Fly   343 IDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKG 407
            :||          .:..::|:. .|:|..|:|.|.:.|....:|             |..|:.|.
Zfish   149 VDS----------SISSSAEVG-KCISRNGHPEPRIIWFKDDNP-------------LPEEKKKT 189

  Fly   408 EK------LDKDG---YKINSG-----AKSEARLPAVYRAHHNARILCVMEH--PTLKIRQNAS- 455
            ||      |.|:.   |.:.|.     .|::|:  :||.        |::|:  |..:|:|.:|
Zfish   190 EKTYMIHFLVKEASGLYTLTSMLYMHLTKADAK--SVYH--------CIVEYTMPDNQIKQESSD 244

  Fly   456 -LLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNF 519
             ..:.:||:......:....| |::||.:|.::|:.|.||  .|::....|:..:...| |.|..
Zfish   245 NFNISLQYSTENVFFKVKNEG-PIKEGDDVVMQCETDGNP--QPQFDFFKGEKLLEGLG-GTLKK 305

  Fly   520 TSIRREHSGWYKCTSRHLNFQYSS---IGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLE 581
            .||.||.||.|||.:  ::::..|   :...|::....:|:|.||:               |.|.
Zfish   306 KSITREDSGTYKCEA--MDYEADSKVQLHKTLNINVHYIDITVEPE---------------GPLV 353

  Fly   582 VQLGGAVTLQCPQGSLGC----WSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQ 642
            |..|..|.|||...:...    |:   ..|..|..        ||.|:.:.|...|.|:|.|||.
Zfish   354 VSKGDHVELQCKAKASEAHTLQWT---KDSKELSN--------TGVFAKESVTLADGGVYVCVGA 407

  Fly   643 SPTNKKKLEVLQSVTVSVKGAPTV--------------MALNATPVAYPGSPLHLNVEFCANPPA 693
            .| :...|:...::||:|||.|.:              :.||.:.:.:|..      :|...|..
Zfish   408 VP-SVPGLQKQVNITVNVKGQPEIDAPVKGLVDKEGGMVTLNCSALGHPAP------QFIWTPSG 465

  Fly   694 HAARWLHGDRVFT 706
            ..:..:.|:||.:
Zfish   466 KESVTVKGNRVIS 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17716	NP_001286391.1	IG_like	244..332	CDD:214653	14/53 (26%)
		Ig	254..323	CDD:143165	12/44 (27%)
		Ig	359..452	CDD:299845	25/108 (23%)
		Ig_3	477..536	CDD:290638	22/58 (38%)
		IG_like	479..550	CDD:214653	23/73 (32%)
		IG_like	578..660	CDD:214653	25/85 (29%)
bcam	NP_001352817.1	V-set	31..131	CDD:311561	12/44 (27%)
		Ig	138..234	CDD:325142	28/131 (21%)
		Ig_3	267..320	CDD:316449	21/55 (38%)
		Ig_2	351..422	CDD:316418	22/82 (27%)
		Ig_3	428..499	CDD:316449	9/57 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5177
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto40408
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.960