DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17716 and plum

DIOPT Version :9

Sequence 1:	NP_001286391.1	Gene:	CG17716 / 36521	FlyBaseID:	FBgn0000633	Length:	822	Species:	Drosophila melanogaster
Sequence 2:	NP_001163744.1	Gene:	plum / 43197	FlyBaseID:	FBgn0039431	Length:	1298	Species:	Drosophila melanogaster

Alignment Length:	731	Identity:	137/731 - (18%)
Similarity:	240/731 - (32%)	Gaps:	250/731 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 TSTSTAVATTVQATSSSSS-----ATRSSVINETKAKRPRSTLH------LAPEDMQPKPKEPV- 187
            |..||.||..|....:|::     ..:...:......:|.|..:      |.|.: ..:..:|:
  Fly    32 TKESTTVAAAVAQPKNSTALQPYLQIQKHAVTRLTISKPHSPYYLPCIPILTPYN-HDQDNQPIY 95

  Fly   188 -------IIIDDVEE-------FDSGTSTSDLIARKSREEAEEE-------EDEGPLEPRVLPLR 231
                   ::::.|..       :|:||     :...:.|:|..|       ::...:..|:....
  Fly    96 CSWYRNDVVVEQVSYRKNDFFIYDNGT-----LRLPTNEKASGEYYCKIEWDESAVISDRITVEY 155

  Fly   232 PVPPNPYEAEEMSV-VYAEQHSEIKLMCE-VDLDIATSMWY-KNGQVVHAMDRTARVTDYRFIKE 293
            ||....:..::.:. :.|.::..:.|.|. :.:..|...|| .|..:.:  |.:|.:.
  Fly   156 PVLKRLFPGQQQAANISALENKPLVLSCPFLSVPAARFSWYFGNDSLTN--DNSALIL------- 211

  Fly   294 ANGALTITNVMLEDDGKWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVK 358
            .||.|.:.::.||..||::|.|:||.....:.:.:..:.:: ||           ||:  |.| |
  Fly   212 TNGTLILRHLRLEQAGKYKCVAQNTFASKTHRQFIWQLQVE-PK-----------DAT--FYP-K 261

  Fly   359 ENSELNLACVSE----------------GGNPRPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKG 407
            ..:.:....|||                ||:        |||    ..||......::...:...
  Fly   262 NEAGITETAVSEAQLLPAFQNATVFVPAGGS--------VLL----QCHAVADFVPIVWYLQPPN 314

  Fly   408 EKL-----DKDGYKINSGAKSEARLPAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFA 467
            .|:     :...|.|.:.:          .|.|..|..|:....|    ||..:::.   ||...
  Fly   315 NKMVRLSNNSVAYSITNAS----------IARHEGRYSCITPLET----QNFQVIVT---TPPRI 362

  Fly   468 ISRTPGFGYPLREGIEV-------SLKCDVDSNPPSTPRWQKDDGDTPVPQTGDGFLNFTSIRRE 525
            :||.|         :||       :|.|..:.:|..:..|.
  Fly   363 VSRLP---------VEVVYIGLSRTLTCRAEGHPEPSITWY------------------------ 394

  Fly   526 HSGWYKCTSRHLNFQYSSIGYYLS---VRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEV--QLG 585
            |:|      .|||..|:.   |:|   :...|.|...|...|.|:...|..:...|:|..  ||.
  Fly   395 HNG------VHLNSSYTR---YISGNELHVHSFDSKEEGIYQCVARNVAGEDSATGELRFNRQLE 450

  Fly   586 GAVTLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSP-----T 645
            ....||    ::.|:.|    |.....:.:.|...|..|    |:|       .|..:|     .
  Fly   451 EVNPLQ----NIRCYPH----SFHSINITFDSRTLTSMF----VVY-------IVRNNPHSWTSF 496

  Fly   646 NKKKLEVLQSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPAHAARWLHGDRVFTPGNQ 710
            :..||.....|.:|..          .||..|.:.:                    .||..|..:
  Fly   497 SPMKLNQTSYVVISTD----------LPVYEPFALI--------------------TRVLFPTTE 531

  Fly   711 Y--GTTV----LAYAVKDLPTPFCKEARL---------TYVSMHE-RVPRTFYFIVSTPGGVAEA 759
            .  ||.|    :..:::..|...|.:..:         |:|...: ::....|||:.
  Fly   532 VRTGTLVPQQMILSSLRSTPVTCCTQGLMLRPIAVGNDTFVKWSQGQLENKKYFILQ-------- 588

  Fly   760 IFNVNFTKRH-RQLSN 774
             |::|.|..| .||.|
  Fly   589 -FSINHTHPHPAQLLN 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17716	NP_001286391.1	IG_like	244..332	CDD:214653	20/90 (22%)
		Ig	254..323	CDD:143165	19/70 (27%)
		Ig	359..452	CDD:299845	18/113 (16%)
		Ig_3	477..536	CDD:290638	8/65 (12%)
		IG_like	479..550	CDD:214653	14/80 (18%)
		IG_like	578..660	CDD:214653	19/88 (22%)
plum	NP_001163744.1	IG_like	170..241	CDD:214653	20/79 (25%)
		IGc2	175..235	CDD:197706	17/68 (25%)
		IG_like	284..356	CDD:214653	17/97 (18%)
		I-set	360..443	CDD:254352	24/124 (19%)
		IGc2	378..435	CDD:197706	17/89 (19%)
		FN3	804..886	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11640
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100