Protein Alignment tei and igcm-2

DIOPT Version :10

• Sequence 1: NP_523731.2
• Gene: tei / 36521
• FlyBaseID: FBgn0000633
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001362087.1
• Gene: igcm-2 / 180913
• WormBaseID: WBGene00020130
• Length: 802
• Species: Caenorhabditis elegans
• Alignment Length: 677
• Identity: 132/677 - (19%)
• Similarity: 225/677 - (33%)
• Gaps: 242/677 - (35%)

  Fly   242 EMSVVYAEQHSEIKLMCEVDLDIATSM---WYKNGQVVHAM--DRTARVT---DYRFIKEANGAL 298
            ||...:.:..:.|.|.|.:.|....|.   |.|:||::.:.  .....||   ..|..::....:
 Worm    19 EMKAYWGKAGAPITLPCSISLFNEESFSLDWRKDGQLILSAFGQEQGHVTPTLQGRLARDGFLGI 83

  Fly   299 TITNVMLEDDGKWQC-----EAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVK 358
            ||.:|...|.|.:||     ..:.||  .|.....||||   ..||.::..|:     |..:..|
 Worm    84 TIHSVTDGDAGVYQCIVTKFSKQPTR--PEKGLSAKLVV---NVPPVIISPSK-----NAIIHKK 138

  Fly   359 ENSELNLACVSEGGNPRPTLTWEVLLSPGVDRHAQKVS-AEVLELEEIKGEKLDKDGYKINSGAK 422
            ..::|...|.:||. |.|.:||        .|:.|.:| :.||.|..:  |:.||..|
 Worm   139 VGADLIFECKAEGA-PSPEITW--------SRNEQIISTSPVLTLSNL--EEGDKGLY------- 185

  Fly   423 SEARLPAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLK 487
                             .|:    .:.|..|::..:||::|.:..:...| ....:.||..|...
 Worm   186 -----------------TCL----AVNIEGNSTSSIDVRFTKATILDLIP-LNKTVIEGSNVFWH 228

  Fly   488 CDVDSNPPS-TPRWQKDDGDTPVPQTG--------DGFLNFTSIRREHSGWYKCTSRH------- 536
            |..::...: :..|..:  ..|:..|.        .|.|:...:|:..||||.|.:::
 Worm   229 CHANAQATAISYSWLFE--KKPIKTTSLGLRSNIRSGDLSLQDVRKSDSGWYTCEAKNSAGETTS 291

  Fly   537 -----------------------------------------LNFQYSSIGYYLSVRFDSVDVTS- 559
                                                     .::.:|..|:||..:..|..:.|
 Worm   292 STAYLHVFYPPEPLSSHQPVQTVASGRNTTVSCDVIANPTPTSYTWSKNGHYLPTQASSHIIISY 356

  Fly   560 -EPDDQDVSVAAASHNPNKG---------------------QLEVQLGGAVTLQCPQGSLGCWSH 602
             :|.|..:....|.:...||                     :::|:||..|::.|.
 Worm   357 AKPGDGGIYGCQADNIAGKGSIVETHLIVAEPPVFTVAPPSEIKVRLGDQVSIPCQ--------- 412

  Fly   603 LDPISARLRGLGYGSSQP------------TGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQS 655
                       |:|...|            ....:.|.|.:.|.|.|:||           |..|
 Worm   413 -----------GFGDPMPIVYWIRDKKRINQSTLTFKKVEHLDHGAYECV-----------VANS 455

  Fly   656 V-TVSVKGAPTVMALNATPVAYPGSPLHLNVEF-CANPPAHAARWLHG-----DRVFTPGNQYGT 713
            | |:|.:    ||.|    |......:..:::| |.|..:....|..|     |:.|....|...
 Worm   456 VETISTR----VMLL----VEITKPQMASSIKFTCLNSSSMRISWTPGYNGGFDQTFAVHAQNDV 512

  Fly   714 TVLAYAVKDLPTPFCKEARLTYVSMHERV-----PRTFYFI----VSTPGGVAEAIFNVNFTKRH 769
            |:...::|              .|::|.:     |...|.:    |:..|       :.|.|..:
 Worm   513 TLQWTSIK--------------TSLNETILDHLEPFVSYRVSIESVNAKG-------STNSTTYN 556

  Fly   770 RQLSNSIDDDEEEELNRPEQIHFPVFN 796
            |:...|        |:.|::::|..:|
 Worm   557 RRSCTS--------LHAPDKLYFCGYN 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tei	NP_523731.2	IG_like	244..332	CDD:214653	24/100 (24%)
		Ig strand B	254..258	CDD:409353	2/3 (67%)
		Ig strand C	267..271	CDD:409353	2/6 (33%)
		Ig strand E	296..300	CDD:409353	0/3 (0%)
		Ig strand F	310..315	CDD:409353	2/9 (22%)
		Ig strand G	326..329	CDD:409353	0/2 (0%)
		Ig	359..452	CDD:472250	20/93 (22%)
		Ig_3	478..533	CDD:464046	14/63 (22%)
		IG_like	578..660	CDD:214653	20/115 (17%)
igcm-2	NP_001362087.1	Ig_3	28..101	CDD:464046	19/72 (26%)
		Ig	124..200	CDD:472250	25/119 (21%)
		Ig strand B	143..147	CDD:409358	1/3 (33%)
		Ig strand C	156..160	CDD:409358	2/11 (18%)
		Ig strand E	171..174	CDD:409358	2/2 (100%)
		Ig strand F	184..189	CDD:409358	2/32 (6%)
		Ig strand G	195..198	CDD:409358	1/2 (50%)
		IG_like	214..298	CDD:214653	16/86 (19%)
		Ig strand C	239..243	CDD:409353	0/3 (0%)
		Ig strand E	263..267	CDD:409353	2/3 (67%)
		Ig strand F	277..282	CDD:409353	3/4 (75%)
		Ig strand G	291..294	CDD:409353	0/2 (0%)
		Ig_3	301..371	CDD:464046	9/69 (13%)
		Ig_3	388..454	CDD:464046	16/96 (17%)
		FN3	476..548	CDD:238020	15/85 (18%)
		FN3	<573..>643	CDD:442628	1/3 (33%)