Protein Alignment tei and LOC1270833

DIOPT Version :10

• Sequence 1: NP_523731.2
• Gene: tei / 36521
• FlyBaseID: FBgn0000633
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: XP_061512903.1
• Gene: LOC1270833 / 1270833
• VectorBaseID: AGAMI1_004438
• Length: 1134
• Species: Anopheles gambiae
• Alignment Length: 1132
• Identity: 523/1132 - (46%)
• Similarity: 641/1132 - (56%)
• Gaps: 316/1132 - (27%)

  Fly     1 MRPTFDRRLWIL-LFIISVQC-------------TTYTQPQNIN---AKSVQKP----------- 37
            |..|.|||:||: |..:.:||             :|...|::.|   .:..|:|
Mosquito     1 MIATIDRRVWIMFLSYLLLQCSLTHILPFTVVLASTIADPEHHNPHQQQQQQQPASNVEDLYHRI 65

  Fly    38 ---------------KPSERREVISTSSSSSHS-WP------------SISAEPA---------- 64
                           :.||.|:.::.|::::.| |.            .|:.||:
Mosquito    66 LDDNEFSSHANVRFNRHSEARDRLAASAAATSSRWQDSTSTQRVNNNRKINLEPSHRSPVPKPSS 130

  Fly    65 -DEVVDHRGGGKPAKCAKNC-------QKAKAKWAKWRTQLK--------PHHQAHRAVQHKEAR 113
             |.|:.  |..:||..:...       |:|..:.......|:        ||..|  .|.|..|.
Mosquito   131 VDSVMS--GLDEPAADSDRAALEDVHEQRALFEREGLSAVLRDAETHGTVPHRVA--PVDHFPAY 191

  Fly   114 QRQRR-----------ETEEDELDAVLRAPSSTSTSTAVATTVQATSSS-SSATRSSVI---NET 163
            :|.||           |:|.::...|..|......:.|...||.|.||: .:..|:|.:   |..
Mosquito   192 RRHRRSLLRRRSIRLKESEGEKPAEVEEASKKPQPNHAPQPTVDANSSAHPNLPRTSGVSSGNPG 256

  Fly   164 KAKRP-------------------------------RSTLHLAP-----EDMQPKP-----KEPV 187
            ||..|                               |:.:.|.|     ....|.|     ..|.
Mosquito   257 KASAPTVPRNTNDNGSASGPTSAKVEHLSTVTGTTERTIMALPPSPSSSSSASPSPHRAAAPHPA 321

  Fly   188 II-------IDDVEEF--------DSGTSTS---------------------------------- 203
            .|       :||....        |||...|
Mosquito   322 AIGIDSFNLLDDSVYIAPAHGLRNDSGGGASARLPTLGTDLTLDASGNIFGRENFDEQIIFLNGP 386

  Fly   204 DL-----------IARKSREEAEEEEDEG----PLEPRVLPLRPV---PPNPYEAEE--MSVVYA 248
            ||           :.:.:||.|.|.|..|    ..||:.|||||:   |.:.:..||  :.||||
Mosquito   387 DLLEPGSAEQGQSVGKVAREVAREVEIVGGGYVADEPQALPLRPIIRGPSDEHNVEEDNVVVVYA 451

  Fly   249 EQHSEIKLMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQC 313
            :||..::|.||||.|:.:|:|.|:||:||.||:.:|..|.||::|..|.|||.||||||||.|||
Mosquito   452 DQHETVRLNCEVDADVTSSVWLKDGQIVHVMDKKSRTADIRFVREPLGGLTIANVMLEDDGVWQC 516

  Fly   314 EAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTL 378
            ||||.|.:..|.||:||:|||.||.||||||||||||.|:|:||||||||.||||||||||:|||
Mosquito   517 EAENARGFFFNGRPIKLIVLDPPKEPYLLIDSRRLDAGNMFIPVKENSELALACVSEGGNPKPTL 581

  Fly   379 TWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARILCVM 443
            |||||||||:||||||:|:|||||:||:.:|.||:.||||:||.||.:||||:|.||||||||:|
Mosquito   582 TWEVLLSPGIDRHAQKISSEVLELQEIQKDKQDKEPYKINAGAVSEVKLPAVFRVHHNARILCIM 646

  Fly   444 EHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQKDDGDTP 508
            ||||||:|||||:||||||||||||:|||||||||||||||||||||||||||||.|||||||.|
Mosquito   647 EHPTLKVRQNASILLDVQYTPSFAITRTPGFGYPLREGIEVSLKCDVDSNPPSTPLWQKDDGDPP 711

  Fly   509 VPQTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASH 573
            |||||||||||:|||||||||||||||||||||||||||||||::.|||||||.:||:.::.:|.
Mosquito   712 VPQTGDGFLNFSSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRYEPVDVTSEPVEQDLPMSPSSS 776

  Fly   574 -------------------------------------------------NPNK-GQLEVQLGGAV 588
                                                             ||.| ||:||:|||:|
Mosquito   777 SSSSSSASSSSSSSSSSVSMPSPGSSLPGGSPNGAVSQPGAAGTDQTGTNPFKAGQMEVELGGSV 841

  Fly   589 TLQCPQGSLGCWSHLDPISARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVL 653
            |||||||||||||||||::|||:|||.|...||||||||||:|||||.||||||:..|:||||||
Mosquito   842 TLQCPQGSLGCWSHLDPMTARLKGLGAGIYTPTGQFSLKDVVYQDAGTYKCVGQNANNRKKLEVL 906

  Fly   654 QSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPAHAARWLHGDRVFTPGNQYGTTVLAY 718
            |:|:::|||||:|.|.|.||||||||||||:|||||||||:||||||||||:||||||||.||||
Mosquito   907 QTVSIAVKGAPSVSARNMTPVAYPGSPLHLSVEFCANPPAYAARWLHGDRVYTPGNQYGTDVLAY 971

  Fly   719 AVKDLPTPFCKEARLTYVSMHERVPRTFYFIVSTPGGVAEAIFNVNFTKRHRQ------------ 771
            ...|||||||||||||||.|||:||||||||||:|||||||:|.||:|.:|:|
Mosquito   972 GFIDLPTPFCKEARLTYVHMHEKVPRTFYFIVSSPGGVAEAVFKVNYTLKHKQMGSGASGAGSGT 1036

  Fly   772 ------LSNSIDD------------------------------DEEEELNRPEQIHFPVF-NGSP 799
                  ||:|:..                              |::|||..||:||||:| .|..
Mosquito  1037 FGSPFSLSSSVSSSSGSGTTVTGGSSGYKINTNTINTVPGNGLDDDEELMEPEEIHFPIFGTGGS 1101

  Fly   800 ADGRGW--WAVVLAL----LLVVATTN 820
            |.||||  .|.|||.    |:|:|.::
Mosquito  1102 AGGRGWVLHAAVLAASSLPLIVMAVSS 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tei	NP_523731.2	IG_like	244..332	CDD:214653	51/87 (59%)
		Ig strand B	254..258	CDD:409353	1/3 (33%)
		Ig strand C	267..271	CDD:409353	2/3 (67%)
		Ig strand E	296..300	CDD:409353	2/3 (67%)
		Ig strand F	310..315	CDD:409353	3/4 (75%)
		Ig strand G	326..329	CDD:409353	2/2 (100%)
		Ig	359..452	CDD:472250	72/92 (78%)
		Ig_3	478..533	CDD:464046	51/54 (94%)
		IG_like	578..660	CDD:214653	62/81 (77%)
LOC1270833	XP_061512903.1	None