DRSC/TRiP Functional Genomics Resources

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Protein Alignment tei and Cntn1

DIOPT Version :10

Sequence 1:NP_523731.2 Gene:tei / 36521 FlyBaseID:FBgn0000633 Length:822 Species:Drosophila melanogaster
Sequence 2:NP_476459.1 Gene:Cntn1 / 117258 RGDID:621300 Length:1021 Species:Rattus norvegicus


Alignment Length:725 Identity:152/725 - (20%)
Similarity:249/725 - (34%) Gaps:184/725 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   162 ETKAKRPRSTLHLA------PEDMQPK---PKEPVIIIDDVEEFDSGTSTSDLIARKSREEAEEE 217
            |.|.|..:..:.|.      |:|:..:   .:.||.|..|...|.|.|:.:..||.      .|.
  Rat   145 EVKVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIAN------VES 203

  Fly   218 EDEG-------------PLEPRVLPLRPVP---PNPYEAE---EMSVVYAEQHSEIKLMC-EVDL 262
            .|.|             .:..:.:||.|:|   ..||.|:   :...:|......:.|.| .:..
  Rat   204 SDRGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDIYTMMGQNVTLECFALGN 268

  Fly   263 DIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGA-LTITNVMLEDDGKWQCEAENTRRYTENAR 326
            .:....|.|   |:..|..||.::       .:|| |.|.|:.|||:|.::|||||.|  .::..
  Rat   269 PVPDIRWRK---VLEPMPTTAEIS-------TSGAVLKIFNIQLEDEGLYECEAENIR--GKDKH 321

  Fly   327 PVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEVLLSPGVDRH 391
            ..::.|...|:....:.|:.....|:|:.|          ||:. |.|.||:.|.          
  Rat   322 QARIYVQAFPEWVEHINDTEVDIGSDLYWP----------CVAT-GKPIPTIRWL---------- 365

  Fly   392 AQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARIL-CVMEHPTLKIRQNAS 455
                                |:||..:.|   |.||..|  ...||.:. |:.|:....|..||.
  Rat   366 --------------------KNGYAYHKG---ELRLYDV--TFENAGMYQCIAENAYGTIYANAE 405

  Fly   456 LLLDVQYTPSFAISRTPGFGYPLR------EGIEVSLKCDVDSNPPSTPRWQKDD----GDTPVP 510
            |.: :...|:|.::       |::      :|..|.::|...:.|.....|.|..    ..:.:.
  Rat   406 LKI-LALAPTFEMN-------PMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRIL 462

  Fly   511 QTGDGFLNFTSIRREHSGWYKCTSRHLNFQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNP 575
            ...||.|...:|.|...|.|.|.:.:...:.:|.|  ..|..:...:...|.:.|::|       
  Rat   463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG--TLVITNPTRIILAPINADITV------- 518

  Fly   576 NKGQLEVQLGGAVTLQC-----PQGSLG-CWS---HLDPISARLRGLGYGSS---QPTGQFSLKD 628
                     |...|:||     |...|. .||   ::...:..:..:.|..:   ...|:..:::
  Rat   519 ---------GENATMQCAASFDPSLDLTFVWSFNGYVIDFNKEITNIHYQRNFMLDANGELLIRN 574

  Fly   629 VMYQDAGMYKCVGQSPTNKKKLEVLQSVTVSVKGAPTVMALNATPVAYPGSPLHLNVEFCANPPA 693
            ...:.||.|.|..|:..:...    .|..:.|:|.             ||.|..|.:| .....:
  Rat   575 AQLKHAGRYTCTAQTIVDNSS----ASADLVVRGP-------------PGPPGGLRIE-DIRATS 621

  Fly   694 HAARWLHGDRVFTPGNQY---GTTVLAYAVKDLPT-PFCKEARLTYVSMHERVP---RTFYFIVS 751
            .|..|..|....:|.::|   ..|:|:...||..| |...|..:......:.:|   ..|..:.:
  Rat   622 VALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLIPWMEYEFRVVAT 686

  Fly   752 TPGGVAEAIFNVNFTKRHRQLSNSIDDD------EEEELN-----RPEQIHFP-----VFNGSPA 800
            ...|..|.....|..|......|....|      ...||.     ...:.|:.     :....|.
  Rat   687 NTLGTGEPSIPSNRIKTDGAAPNVAPSDVGGGGGTNRELTITWAPLSREYHYGNNFGYIVAFKPF 751

  Fly   801 DGRGWWAVVL 810
            ||..|..|.:
  Rat   752 DGEEWKKVTV 761

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
teiNP_523731.2 IG_like 244..332 CDD:214653 24/89 (27%)
Ig strand B 254..258 CDD:409353 1/3 (33%)
Ig strand C 267..271 CDD:409353 1/3 (33%)
Ig strand E 296..300 CDD:409353 3/4 (75%)
Ig strand F 310..315 CDD:409353 1/4 (25%)
Ig strand G 326..329 CDD:409353 0/2 (0%)
Ig 359..452 CDD:472250 20/93 (22%)
Ig_3 478..533 CDD:464046 13/64 (20%)
IG_like 578..660 CDD:214653 16/93 (17%)
Cntn1NP_476459.1 IgI_1_Contactin-1 40..134 CDD:409436
Ig strand A 42..46 CDD:409436
Ig strand A' 49..54 CDD:409436
Ig strand B 60..68 CDD:409436
Ig strand C 73..79 CDD:409436
Ig strand C' 81..84 CDD:409436
Ig strand D 90..94 CDD:409436
Ig strand E 96..102 CDD:409436
Ig strand F 109..118 CDD:409436
Ig strand G 121..134 CDD:409436
Ig2_Contactin-2-like 142..230 CDD:409392 19/90 (21%)
Ig strand A 144..149 CDD:409392 2/3 (67%)
Ig strand B 153..159 CDD:409392 1/5 (20%)
Ig strand C 168..174 CDD:409392 0/5 (0%)
Ig strand C' 179..181 CDD:409392 1/1 (100%)
Ig strand D 186..191 CDD:409392 1/4 (25%)
Ig strand E 194..198 CDD:409392 0/3 (0%)
Ig strand F 208..216 CDD:409392 0/7 (0%)
Ig strand G 218..230 CDD:409392 1/11 (9%)
IgI_3_Contactin-1 241..328 CDD:143259 25/98 (26%)
Ig strand A 241..246 CDD:143259 1/4 (25%)
Ig strand A' 249..254 CDD:143259 1/4 (25%)
Ig strand B 257..266 CDD:143259 2/8 (25%)
Ig strand C 272..276 CDD:143259 0/3 (0%)
Ig strand C' 279..281 CDD:143259 0/1 (0%)
Ig strand D 289..292 CDD:143259 0/9 (0%)
Ig strand E 293..298 CDD:143259 2/4 (50%)
Ig strand F 306..314 CDD:143259 4/7 (57%)
Ig strand G 317..328 CDD:143259 0/10 (0%)
Ig 332..408 CDD:472250 27/121 (22%)
Ig strand B 348..352 CDD:409353 2/13 (15%)
Ig strand C 361..365 CDD:409353 1/3 (33%)
Ig strand E 374..378 CDD:409353 2/6 (33%)
Ig strand F 388..393 CDD:409353 1/4 (25%)
Ig strand G 401..404 CDD:409353 0/2 (0%)
Ig5_Contactin-1 413..501 CDD:409438 19/96 (20%)
Ig strand A 413..418 CDD:409438 2/4 (50%)
Ig strand A' 421..426 CDD:409438 0/4 (0%)
Ig strand B 430..437 CDD:409438 1/6 (17%)
Ig strand C 445..449 CDD:409438 0/3 (0%)
Ig strand D 463..466 CDD:409438 0/2 (0%)
Ig strand E 467..472 CDD:409438 2/4 (50%)
Ig strand F 480..488 CDD:409438 3/7 (43%)
Ig strand G 494..501 CDD:409438 2/8 (25%)
Ig6_Contactin 503..603 CDD:409359 19/119 (16%)
Ig strand A 503..509 CDD:409359 0/5 (0%)
Ig strand A' 512..517 CDD:409359 1/4 (25%)
Ig strand B 520..528 CDD:409359 3/7 (43%)
Ig strand C 537..541 CDD:409359 0/3 (0%)
Ig strand D 564..567 CDD:409359 0/2 (0%)
Ig strand E 568..572 CDD:409359 1/3 (33%)
Ig strand F 581..588 CDD:409359 3/6 (50%)
Ig strand G 595..599 CDD:409359 1/7 (14%)
FN3 612..699 CDD:238020 18/87 (21%)
FN3 650..>947 CDD:442628 21/112 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 695..719 4/23 (17%)
fn3 813..895 CDD:394996
FN3 907..991 CDD:238020
Blue background indicates that the domain is not in the aligned region.

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