Protein Alignment CG6209 and CYLC1

DIOPT Version :10

• Sequence 1: NP_610894.1
• Gene: CG6209 / 36517
• FlyBaseID: FBgn0033862
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_066941.1
• Gene: CYLC1 / 1538
• HGNCID: 2582
• Length: 651
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 122/563 - (21%)
• Similarity: 212/563 - (37%)
• Gaps: 114/563 - (20%)

  Fly   136 PKP---------EPKKKCSRISRKRKHLLEQKKKAA----KSEAPPESQSEPNLDEAVDELKFSC 187
            |||         .|.|....::|..|..||:.:|.|    :.......|..|....|.::..|..
Human    38 PKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWIRHSFRKILQWPPIYTAAREQTPFRH 102

  Fly   188 MLASEKKDCERKQYKALCEELRKSKPQ--GDPKSVDSLVKCMLSGIQKACIVHAEKIVYQK---- 246
            :..| |...::.:||       |||.:  |.|...||..|    |...|....:::||.:|
Human   103 LYTS-KTHLKKAEYK-------KSKDEKGGTPLKKDSKKK----GGSYATNPESKQIVEEKTKRQ 155

  Fly   247 KFAEQIAIEEAKRKEREKKEGKPLDCTKPSEDDETGAKNKAEKKKAKEKAEIKRLLKEIKGKCKK 311
            ..|::..::.:...|:.||.....:....|::.:|.:||.::|.| |:....|:...|.......
Human   156 NEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDK-KDSKNSKKTNTEFLHTKNN 219

  Fly   312 QREEAERKKKEEAELNKKCKEAAAKKKCEELEAKKKCE----EAAAKKKCEEAAAKKKCEEAAAK 372
            .:::.:|.|.....:::.|.|.:.......|..:...|    :|..:...:..:.....:.....
Human   220 PKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYT 284

  Fly   373 KKCEEAAAKKKCEEAAAKKKCEEAAAKKKCEEAAAKKKCEEAAAKKKCEKSAPKNKCQESAAKNK 437
            ||..:..|||..:..:...|..:..:||      .||..::...||..:|.......:...:|::
Human   285 KKDTKKNAKKSSDAESEDSKDAKKDSKK------VKKNVKKDDKKKDVKKDTESTDAESGDSKDE 343

  Fly   438 CKEAAAKKNCAEAEAKKK----------CEEAAAKKKCEEAAAKKKCEEAAAKKK---------- 482
            .|:....|...:.:.|||          .|...||....::...||..:...|||
Human   344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTD 408

  Fly   483 CEEAAAKKKCEEGAAKKKCEEKAEIKKCVESDRKKNSAND---AAMKKCEEDKKKKSQEAEKKTK 544
            .|.....|:.::...|.|.:.|.:.||.|::|.:...|:.   ...||.::|:||..::::|..|
Human   409 SESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDK 473

  Fly   545 SEQAALQKKCAEA---------KKNKAREAEKK--KKTAESERKKDCDL--AEFKKRCNE----- 591
            .:.|   ||.||:         ||:|....|||  ||..:.:.:||.:.  |||.:....
Human   474 KKDA---KKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTS 535

  Fly   592 ------------------LKKKIAEAN----------CEEKKG 606
                              .||||.|::          .|.|:|
Human   536 TKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRG 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6209	NP_610894.1	PTZ00121	<246..>607	CDD:173412	91/438 (21%)
CYLC1	NP_066941.1	Cylicin_N	8..114	CDD:464581	17/76 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..241		31/142 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	267..615		70/321 (22%)
		8 X approximate tandem repeats	532..553		0/20 (0%)