DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6191 and Cables2

DIOPT Version :9

Sequence 1:	NP_001260958.1	Gene:	CG6191 / 36513	FlyBaseID:	FBgn0027581	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_008760807.1	Gene:	Cables2 / 311703	RGDID:	1310089	Length:	589	Species:	Rattus norvegicus

Alignment Length:	412	Identity:	135/412 - (32%)
Similarity:	202/412 - (49%)	Gaps:	68/412 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 GGVAGGAGSKLLPLRERTFSNGASDQNLQPERRARLNTAPGMRVGSNSSIAMGGGLKRTYVLS-G 329
            ||:.|      ||.|.      |....|.|      .|||       :|:.:.|..:|..|.| .
  Rat    87 GGLPG------LPARP------APQGLLSP------TTAP-------ASLGLDGQRQRRRVTSQR 126

  Fly   330 SSVSHITDDSSTESLTPAGNYAGSFRN-SLSKSVQISDSRRGTSGQPLGLGQARDERMVLVSRKI 393
            .|:..:.|.....|:....:.:||.|: .|.|:..|.:.|:         ...::.|:||:..|.
  Rat   127 CSLEFLEDAVGCASVQRTKHASGSPRHKGLKKTHFIKNMRQ---------YDTKNSRIVLICAKR 182

  Fly   394 PF-FIFSSLPYYKGKNGRAEFRKEDRRRRNPSTSRPLSSINDAPFDPFDLLGIQKAESGQDISYG 457
            .. ..||.|||.:|.. .::.|.:.:::|:||......|::....  |:|.|::....|:.:||.
  Rat   183 SLCAAFSVLPYGEGLR-ISDLRVDSQKQRHPSGGGGGVSVSSEMV--FELEGVELGADGKVVSYA 244

  Fly   458 HLLIPSRQYEKERK-KHG-NASANPSIFENQMEITSTAALKNHGIARCFTYENNNRNSATSPTPD 520
            ..|.|:......:. .|| .....|||                        ......|...|.|.
  Rat   245 KFLYPTNALVTHKNDSHGLLPQPRPSI------------------------PRAPPGSRHKPVPT 285

  Fly   521 MKLDMDIESVILGGDSSRGQVYSASILDDPELIAGKHRTLLTFTSYMTSVIDYVRPSDLKKELND 585
            .......|....|.|......|:.::||||:...|||:.:|.|.||||:||:||:|:||||::|:
  Rat   286 KSTPAGTELGSTGSDGGDAVEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPADLKKDMNE 350

  Fly   586 KFREKFPTIQLTLSKLRSIKREMRRINKLDSRIDLVTISQAYVYFEKLILANLINKSNRKLCAGA 650
            .||||||.|:|||||:||:|||||.::: :..::.||:|.||||||||.|...:||.||||||||
  Rat   351 TFREKFPHIKLTLSKIRSLKREMRNLSE-ECSLEPVTVSMAYVYFEKLALQGKLNKQNRKLCAGA 414

  Fly   651 CLLLSAKM-NDVKGDALKSLIE 671
            |:||:||: :|::...:|.||:
  Rat   415 CVLLAAKISSDLRKSEVKQLID 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6191	NP_001260958.1	CYCLIN	579..699	CDD:294043	54/94 (57%)
Cables2	XP_008760807.1	CYCLIN	366..444	CDD:238003	38/72 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334405
Domainoid	1	1.000	132	1.000	Domainoid score	I4980
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3177
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002600
OrthoInspector	1	1.000	-	-		otm44788
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22896
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2314
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.990