Protein Alignment CG13334 and Mdh1b

DIOPT Version :10

• Sequence 1: NP_610888.2
• Gene: CG13334 / 36510
• FlyBaseID: FBgn0033856
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: XP_036010132.1
• Gene: Mdh1b / 76668
• MGIID: 1923918
• Length: 501
• Species: Mus musculus
• Alignment Length: 295
• Identity: 60/295 - (20%)
• Similarity: 101/295 - (34%)
• Gaps: 94/295 - (31%)

  Fly    28 SVKSCFAKSMRPMKEFKRPRISK-----ISVVGAGQVGTAISAMLLLR---NLTKNLVILDINYE 84
            |::||. :|..|:.......|.|     :.|:..|:....:...||::   |:..|::.:.:..|
Mouse   224 SLESCL-RSRVPLCRLYGYLIEKNAHKSVKVIVGGKNFVNLKTTLLMQYAPNIASNIIAVALGVE 287

  Fly    85 -LAKAE-ALDFQHASAFLSDARVVPCGDSTNSKDSDV------VIITAGARPSGKDRSRLAAMQK 141
             .|||. |...:..||.:.|  |:..|:.|.:...|:      ...:|...|.|...|.|:.:..
Mouse   288 GQAKAVLARKMKTTSANIKD--VIIWGNITGNNYVDLRKAKVYNYESAVKGPPGHYHSVLSLIFD 350

  Fly   142 TVEILKKAVPKLVELSPNATFIIISNPADVMTYAVQRITNLPKHRCFTTGCHLDTVRFRNLIANR 206
            ...|.|:.|..|..||                               :||.....:...:.||..
Mouse   351 REWITKEFVQTLKILS-------------------------------STGKQFGGILAAHSIATT 384

  Fly   207 LRL-----PPSQVHGYVIGEHGASAVP--------------VW------SSVSIAGIRLN----D 242
            |:.     ||.::....:...|...:|              .|      ..:|::...|:    |
Mouse   385 LKYWYHGSPPGEIVSLGVMSEGQFDIPEGIVFSMPVKFENGTWVVLTDLEDISLSEKTLSRLTGD 449

  Fly   243 VV--KNLACGD---------DPENWAKINKQVTTG 266
            ::  |.:||||         ||    |.|:...||
Mouse   450 LIQEKLVACGDLLTFQPIEEDP----KDNEPSNTG 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13334	NP_610888.2	LDH_1	46..358	CDD:133429	55/277 (20%)
Mdh1b	XP_036010132.1	Rossmann-fold NAD(P)(+)-binding proteins	9..459	CDD:473865	51/268 (19%)