Protein Alignment CG13334 and MDH2

DIOPT Version :10

• Sequence 1: NP_610888.2
• Gene: CG13334 / 36510
• FlyBaseID: FBgn0033856
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_005909.2
• Gene: MDH2 / 4191
• HGNCID: 6971
• Length: 338
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 82/341 - (24%)
• Similarity: 128/341 - (37%)
• Gaps: 97/341 - (28%)

  Fly    49 SKISVVGA-GQVGTAISAMLLLRN--LTKNLVILDINYELAKAEALDFQH------ASAFLSDAR 104
            :|::|:|| |.:|..:|  |||:|  |...|.:.||.:  ....|.|..|      ...:|...:
Human    25 AKVAVLGASGGIGQPLS--LLLKNSPLVSRLTLYDIAH--TPGVAADLSHIETKAAVKGYLGPEQ 85

  Fly   105 VVPCGDSTNSKDSDVVIITAGA-RPSGKDRSRLAAMQKTVEILKKAVPKLVELSPNATFIIISNP 168
            :..|     .|..|||:|.||. |..|..|..|.....|  |:........:..|.|...:|:||
Human    86 LPDC-----LKGCDVVVIPAGVPRKPGMTRDDLFNTNAT--IVATLTAACAQHCPEAMICVIANP 143

  Fly   169 ADVMTYAVQRITNLP-------KHRCF--------TTGCHLDTVRFRNLIANRLRLPPSQVHGYV 218
            .:         :.:|       ||..:        ||   ||.||....:|....|.|::|:..|
Human   144 VN---------STIPITAEVFKKHGVYNPNKIFGVTT---LDIVRANTFVAELKGLDPARVNVPV 196

  Fly   219 IGEH-GASAVPVWSSVSIAGIRLNDVVKNLACG---DDPEN-WAKINKQVTTGGLAVAKTK---G 275
            ||.| |.:.:|:.|.                |.   |.|:: ...:..::...|..|.|.|   |
Human   197 IGGHAGKTIIPLISQ----------------CTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAG 245

  Fly   276 YTNWAIALTCA----DIVQAMSGGKGKIACVGTD-------------MKGLNGIQDNVVLSLPCL 323
            ....::|...|    .:|.||:|.:|.:.|....             :.|..||:.|:.:
Human   246 SATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGI----- 305

  Fly   324 VTAGGISHVFELPLTD 339
               |.:|...|..::|
Human   306 ---GKVSSFEEKMISD 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13334	NP_610888.2	LDH_1	46..358	CDD:133429	82/341 (24%)
MDH2	NP_005909.2	MDH_glyoxysomal_mitochondrial	26..334	CDD:133422	82/340 (24%)