Protein Alignment Roe1 and GRPEL1

DIOPT Version :9

• Sequence 1: NP_610886.2
• Gene: Roe1 / 36508
• FlyBaseID: FBgn0014877
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_079472.1
• Gene: GRPEL1 / 80273
• HGNCID: 19696
• Length: 217
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 101/212 - (47%)
• Similarity: 133/212 - (62%)
• Gaps: 7/212 - (3%)

  Fly     3 AKAALP-LQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEATEQKATESSPEVEKLTKELAAAK 66
            |:.:|| |.:..|....|..:.|.|..|...|.....|.|:..:..|||.:     |.:|....:
Human     9 ARRSLPALALSLRPSPRLLCTATKQKNSGQNLEEDMGQSEQKADPPATEKT-----LLEEKVKLE 68

  Fly    67 EQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKDKL-SG 130
            ||..|.::||||:|||:||:|.|..|.:.:||::|||:||||||||||.|..|||.|||::: ..
Human    69 EQLKETVEKYKRALADTENLRQRSQKLVEEAKLYGIQAFCKDLLEVADVLEKATQCVPKEEIKDD 133

  Fly   131 NADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKEDKTVEPNTVVEVTKLG 195
            |..||||||||.||...:.:||.:|||..|:|:..||||.:|||||....:..||.||..|:|:|
Human   134 NPHLKNLYEGLVMTEVQIQKVFTKHGLLKLNPVGAKFDPYEHEALFHTPVEGKEPGTVALVSKVG 198

  Fly   196 YKLHERCIRPALVGVSK 212
            ||||.|.:|||||||.|
Human   199 YKLHGRTLRPALVGVVK 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Roe1	NP_610886.2	GrpE	70..210	CDD:271355	79/140 (56%)
		2-helical coiled coil	70..120	CDD:271355	29/49 (59%)
		2-helical coiled coil	140..155	CDD:271355	6/14 (43%)
GRPEL1	NP_079472.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..56		6/26 (23%)
		GrpE	72..213	CDD:271355	79/140 (56%)
		2-helical coiled coil	72..122	CDD:271355	29/49 (59%)
		2-helical coiled coil	143..158	CDD:271355	6/14 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147769
Domainoid	1	1.000	174	1.000	Domainoid score	I3691
eggNOG	1	0.900	-	-		E1_COG0576
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6992
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4037
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61230
OrthoDB	1	1.010	-	-		D1525208at2759
OrthoFinder	1	1.000	-	-		FOG0001525
OrthoInspector	1	1.000	-	-		otm42146
orthoMCL	1	0.900	-	-		OOG6_100642
Panther	1	1.100	-	-	LDO	PTHR21237
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R526
SonicParanoid	1	1.000	-	-		X1249
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800