DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Roe1 and grpel1

DIOPT Version :9

Sequence 1:	NP_610886.2	Gene:	Roe1 / 36508	FlyBaseID:	FBgn0014877	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_001016179.1	Gene:	grpel1 / 548933	XenbaseID:	XB-GENE-973857	Length:	216	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	100/209 - (47%)
Similarity:	134/209 - (64%)	Gaps:	11/209 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QMFGRRLVHLRSSVTS-QNMSALRLYSTEKQ----PEEATEQKATESSPEVEKLTKELAAAKEQN 69
            |.||   ..|||:.|. :....|...:|::|    .:|...:..||.||  ::...|.|..::|.
Frog    11 QSFG---AVLRSAQTPVRTCPRLMCTATKEQNNPTQDEDKSKNQTEESP--DQAATEKAKLEDQI 70

  Fly    70 AELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKDKLSG-NAD 133
            .:|.|||||:|||:||:|.|..|.:.:||::|||.||||||||||.|..||::|||.::.. |..
Frog    71 KDLTDKYKRALADTENLRQRSKKLVDEAKLYGIQGFCKDLLEVADILEKATESVPKAEIKAENPH 135

  Fly   134 LKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKEDKTVEPNTVVEVTKLGYKL 198
            ||||||||.||...:.:|.|:||:..|:|:..||:|.:|||||....:..||.||..|||:||||
Frog   136 LKNLYEGLIMTEVQMQKVLKKHGVVKLNPVGDKFNPYEHEALFHSPVEGKEPGTVALVTKVGYKL 200

  Fly   199 HERCIRPALVGVSK 212
            |||.:|||||||.|
Frog   201 HERTLRPALVGVVK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Roe1	NP_610886.2	GrpE	70..210	CDD:271355	79/140 (56%)
		2-helical coiled coil	70..120	CDD:271355	30/49 (61%)
		2-helical coiled coil	140..155	CDD:271355	6/14 (43%)
grpel1	NP_001016179.1	GrpE	71..212	CDD:271355	79/140 (56%)
		2-helical coiled coil	71..121	CDD:271355	30/49 (61%)
		2-helical coiled coil	142..157	CDD:271355	6/14 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3668
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6992
Inparanoid	1	1.050	175	1.000	Inparanoid score	I3951
OMA	1	1.010	-	-		QHG61230
OrthoDB	1	1.010	-	-		D1525208at2759
OrthoFinder	1	1.000	-	-		FOG0001525
OrthoInspector	1	1.000	-	-		oto105253
Panther	1	1.100	-	-	LDO	PTHR21237
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R526
SonicParanoid	1	1.000	-	-		X1249
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110