Protein Alignment Roe1 and Grpel2

DIOPT Version :9

• Sequence 1: NP_610886.2
• Gene: Roe1 / 36508
• FlyBaseID: FBgn0014877
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_067271.1
• Gene: Grpel2 / 17714
• MGIID: 1334416
• Length: 224
• Species: Mus musculus
• Alignment Length: 231
• Identity: 84/231 - (36%)
• Similarity: 121/231 - (52%)
• Gaps: 34/231 - (14%)

  Fly     1 MSAKAALPLQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEATEQKATESSPE----------- 54
            |:|::...:|...|.|.   |...|::...|..:||..| ..|.|..::|..|:
Mouse     1 MAARSLWAVQRLQRLLA---SGAMSESRGWLHPFSTATQ-RTAGEDCSSEDPPDGLGPSLAEQAL 61

  Fly    55 ---VEKLTKELAAAKEQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTL 116
               ..||.||:       .:|..:|:|::||.||:|.|..:.:.||||||||||||||:||||.|
Mouse    62 RLKAVKLEKEV-------QDLTLRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADIL 119

  Fly   117 GHATQ-----AVPKDKLSGNADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEAL- 175
            ....:     |.|:|.   ...|:.:::||::..|.|..||.:||||.:.||..|:||::||.:
Mouse   120 EKTAKCCSEGAEPEDH---RRTLEKVFQGLSLLEARLKSVFTKHGLEKMTPIGDKYDPHEHELIC 181

  Fly   176 FQKEDKTVEPNTVVEVTKLGYKLHERCIRPALVGVS 211
            .......|:|.||..|.:.|||||.|.||.|.|.|:
Mouse   182 HMPAGVGVQPGTVALVRQDGYKLHGRTIRLAQVEVA 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Roe1	NP_610886.2	GrpE	70..210	CDD:271355	64/145 (44%)
		2-helical coiled coil	70..120	CDD:271355	28/49 (57%)
		2-helical coiled coil	140..155	CDD:271355	6/14 (43%)
Grpel2	NP_067271.1	GrpE	73..216	CDD:271355	64/145 (44%)
		2-helical coiled coil	73..123	CDD:271355	28/49 (57%)
		2-helical coiled coil	145..160	CDD:271355	6/14 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0576
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61230
OrthoDB	1	1.010	-	-		D1525208at2759
OrthoFinder	1	1.000	-	-		FOG0001525
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100642
Panther	1	1.100	-	-	O	PTHR21237
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1249
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.720