Protein Alignment Roe1 and Grpel1

DIOPT Version :10

• Sequence 1: NP_610886.2
• Gene: Roe1 / 36508
• FlyBaseID: FBgn0014877
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_077798.1
• Gene: Grpel1 / 17713
• MGIID: 1334417
• Length: 217
• Species: Mus musculus
• Alignment Length: 213
• Identity: 102/213 - (47%)
• Similarity: 133/213 - (62%)
• Gaps: 9/213 - (4%)

  Fly     3 AKAALP-LQMFGRRLVHLRSSVTSQNMSALRLYSTEKQPEEATEQKATESSPEVEK-LTKELAAA 65
            |:.:|| |.:..|....|..:.|.|..:...|      .|:....:.....|..:| |.:|.|..
Mouse     9 ARRSLPALALSFRPSPRLLCTATKQKNNGQNL------DEDLGHCEPKTDPPSADKTLLEEKAKL 67

  Fly    66 KEQNAELMDKYKRSLADSENMRNRLNKQISDAKIFGIQSFCKDLLEVADTLGHATQAVPKDKLS- 129
            :||..|.|:||||:|||:||:|.|..|.:.:||::|||.||||||||||.|..|||:|||:::|
Mouse    68 EEQLRETMEKYKRALADTENLRQRSQKLVEEAKLYGIQGFCKDLLEVADILEKATQSVPKEEISN 132

  Fly   130 GNADLKNLYEGLTMTRASLLQVFKRHGLEPLDPINQKFDPNQHEALFQKEDKTVEPNTVVEVTKL 194
            .|..||:|||||.||...:.:||.:|||..||||..||||.:|||||....:..||.||..|:|:
Mouse   133 NNPHLKSLYEGLVMTEVQIQKVFTKHGLLRLDPIGAKFDPYEHEALFHTPVEGKEPGTVALVSKV 197

  Fly   195 GYKLHERCIRPALVGVSK 212
            |||||.|.:|||||||.|
Mouse   198 GYKLHGRTLRPALVGVVK 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Roe1	NP_610886.2	GrpE	70..210	CDD:271355	82/140 (59%)
		2-helical coiled coil	70..120	CDD:271355	30/49 (61%)
		2-helical coiled coil	140..155	CDD:271355	6/14 (43%)
Grpel1	NP_077798.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..56		3/24 (13%)
		GrpE	72..213	CDD:271355	82/140 (59%)
		2-helical coiled coil	72..122	CDD:271355	30/49 (61%)
		2-helical coiled coil	143..158	CDD:271355	6/14 (43%)