Protein Alignment Nadk1b and NADK

DIOPT Version :10

• Sequence 1: NP_788346.1
• Gene: Nadk1b / 36507
• FlyBaseID: FBgn0053156
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001185923.1
• Gene: NADK / 65220
• HGNCID: 29831
• Length: 591
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 247/580 - (42%)
• Similarity: 314/580 - (54%)
• Gaps: 172/580 - (29%)

  Fly    53 LQRKVQPDHNGNCLA--------------RGRSRENANAIDSSSSGGGRRRRSGTWPRTRSLNAP 103
            :.:::.||....|.:              |||::  :.::.:|.:.|..:.    :.|||||:.|
Human    10 MNKELSPDAAAYCCSACHGDETWSYNHPIRGRAK--SRSLSASPALGSTKE----FRRTRSLHGP 68

  Fly   104 SPVQQFGPCGRIMKNSAMVM--------------------------------------------- 123
            .||..|||...:::|...::
Human    69 CPVTTFGPKACVLQNPQTIIATPLSLASQLLPSPAVSHSGQGGVTGQVHVLPQPSDQGVLSGPRA 133

  Fly   124 -----------------------------------------------------------QIQDPA 129
                                                                       .|||||
Human   134 ARGQTAPQEEAVTQEEVEALVCGHTQRWVPGPVYDAAAGGSGWAQLSLRAGMGVGQATGHIQDPA 198

  Fly   130 SQRLTWYKPPLTVLVIKKVSDASVLAPFVYLVDWLLQ---------------------------- 166
            ||||||.|.|.:||||||:.|||:|.||..|...|::
Human   199 SQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEARGAGGKGAWGAHGVGGASIHITAPRVG 263

  Fly   167 ------------EKNMVVWVESAVLEDVQLNENVRFKAIRDKLVTFKDGRDDLTDRIDFIVCLGG 219
                        ::||:|:||..||||..:..:..|.|::.|..||::..||::::||||:||||
Human   264 SAGGMSRLALCFQENMIVYVEKKVLEDPAIASDESFGAVKKKFCTFREDYDDISNQIDFIICLGG 328

  Fly   220 DGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRL--RCVMHR 282
            ||||||||.|||.|||||||||||||||||||.|:||:.|:|.|:||:||:.|||||  |.|...
Human   329 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQSQVTQVIEGNAAVVLRSRLKVRVVKEL 393

  Fly   283 RSDRK--H----EAKTLEADLDGEARPAANSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQG 341
            |..:.  |    |..:..|.||.:....|....||||||||||||.||||:|::|||..||:|||
Human   394 RGKKTAVHNGLGENGSQAAGLDMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQG 458

  Fly   342 DGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTS 406
            ||:||||||||||||||||||||||:|||||:|||||||||||||||||||||||.:|||:|||:
Human   459 DGVIVSTPTGSTAYAAAAGASMIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTA 523

  Fly   407 WVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQISDWFASLADGLHWNVRKRQKCLDE 466
            |||||||.|||:.||||:.:|||.||:|.||.:|.:||||.|||..|||||||:|...:|
Human   524 WVSFDGRKRQEIRHGDSISITTSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFEE 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nadk1b	NP_788346.1	DAGK_cat	<133..461	CDD:445337	217/375 (58%)
NADK	NP_001185923.1	pnk	<200..578	CDD:333282	219/377 (58%)