DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6145 and NADK2

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001185057.1	Gene:	NADK2 / 838766	AraportID:	AT1G21640	Length:	999	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	166/500 - (33%)
Similarity:	243/500 - (48%)	Gaps:	124/500 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 HTANRASTRAKDQASTDD-------------CVATSPGNIQAKSEQDPD------DGYFDSTTRR 101
            |:...:.|:..:..|:.|             | |::.|.::.:|.:..:      ||...:..:.
plant   591 HSVRESQTQRNNSGSSSDSSDDEAGAIEGNMC-ASATGVVRVQSRKKAEMFLVRTDGVSCTREKV 654

  Fly   102 TRSG---TWPRTRSLNAPSPFQHFGPCGRIMKNSAMVMQIQDPASQRLTWYKPPLTVLVIKKKDS 163
            |.|.   |.|.|:                               .|.|.|...|.|||::||...
plant   655 TESSLAFTHPSTQ-------------------------------QQMLLWKTTPKTVLLLKKLGQ 688

  Fly   164 QVLPPFVQLVEWLVQEKHMVVWVESAVLEDKLLRDDVKLEQESSKFQK------VHQQYAGVRAR 222
                   :|:|...:|.|           :|||...:..:..|..:.:      |..:...|.||
plant   689 -------ELMEEAKEEVH-----------EKLLVFQICFQAASFLYHQENMNVLVEPEVHDVFAR 735

  Fly   223 FLDLREKLVTFKDGRDDLTDRIDFIVCLGGDGTLLYASQLFQQSVPPVMAFYLGSLGFLTPFQCD 287
            ..........:.....||.:|:||:.||||||.:|:||.||:.:||||::|.||||||||....:
plant   736 IPGFGFVQTFYIQDTSDLHERVDFVACLGGDGVILHASNLFKGAVPPVVSFNLGSLGFLTSHPFE 800

  Fly   288 NFQEQVTNVLEGHAAL-----TLRSRLRCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELN 347
            :|::.:..|:.|:..|     |||.||||.|:|||:
plant   801 DFRQDLKRVIHGNNTLDGVYITLRMRLRCEIYRKGK----------------------------- 836

  Fly   348 NGQTGKAGSNNNNGHNNSILVLNEVVINRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTA 412
             ...||...           ||||:|::||.:||||.|:.:...:.||.|||||:||:|||||||
plant   837 -AMPGKVFD-----------VLNEIVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTA 889

  Fly   413 YAAAAGASMIHPSVPAILVTPICPHSLSFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELN 477
            |:.|||.||:||:||.:|.||||||||||||:::|...:|::.|..|:|:.:.|||||:..|:|:
plant   890 YSTAAGGSMVHPNVPCMLFTPICPHSLSFRPVILPDSAKLELKIPDDARSNAWVSFDGKRRQQLS 954

  Fly   478 HGDSLRVTTSIYPVPSICSQDQISDWFDSLAEGLHWNVRKRQKCL 522
            .|||:|:..|.:|:|::...||..|||.||...|:||.|..||.|
plant   955 RGDSVRIYMSQHPLPTVNKSDQTGDWFRSLIRCLNWNERLDQKAL 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	147/383 (38%)
NADK2	NP_001185057.1	PLN02727	13..999	CDD:215386	165/498 (33%)
NADK2	NP_001185057.1	DAGK_cat	<665..998	CDD:294771	150/422 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	238	1.000	Domainoid score	I599
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263874at2759
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		mtm1049
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.680