Protein Alignment CG6145 and NADK

DIOPT Version :9

• Sequence 1: NP_725314.1
• Gene: CG6145 / 36506
• FlyBaseID: FBgn0033853
• Length: 548
• Species: Drosophila melanogaster
• Sequence 2: NP_001185923.1
• Gene: NADK / 65220
• HGNCID: 29831
• Length: 591
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 219/429 - (51%)
• Similarity: 282/429 - (65%)
• Gaps: 81/429 - (18%)

  Fly   138 IQDPASQRLTWYKPPLTVLVIKK-KDSQVLPPFVQLVEWLVQ----------------------- 178
            |||||||||||.|.|.:|||||| :|:.:|.||.:|...|::
Human   194 IQDPASQRLTWNKSPKSVLVIKKMRDASLLQPFKELCTHLMEARGAGGKGAWGAHGVGGASIHIT 258

  Fly   179 -----------------EKHMVVWVESAVLEDKLLRDDVKLEQESSKFQKVHQQYAGVRARFLDL 226
                             :::|:|:||..||||..:..|     ||                |..:
Human   259 APRVGSAGGMSRLALCFQENMIVYVEKKVLEDPAIASD-----ES----------------FGAV 302

  Fly   227 REKLVTFKDGRDDLTDRIDFIVCLGGDGTLLYASQLFQQSVPPVMAFYLGSLGFLTPFQCDNFQE 291
            ::|..||::..||::::||||:||||||||||||.|||.||||||||:||||||||||..:|||.
Human   303 KKKFCTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFSFENFQS 367

  Fly   292 QVTNVLEGHAALTLRSRLRCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGS 356
            |||.|:||:||:.|||||:..:.::...:|.::.:.:|                 .||... ||.
Human   368 QVTQVIEGNAAVVLRSRLKVRVVKELRGKKTAVHNGLG-----------------ENGSQA-AGL 414

  Fly   357 NNNNGHN-NSILVLNEVVINRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGAS 420
            :.:.|.. ....|||||||:||||.||||:|::|:|..||:|||||:||||||||||||||||||
Human   415 DMDVGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGAS 479

  Fly   421 MIHPSVPAILVTPICPHSLSFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVT 485
            ||||:||||::|||||||||||||||||||||||.:||::|||:.||||||..||:.||||:.:|
Human   480 MIHPNVPAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISIT 544

  Fly   486 TSIYPVPSICSQDQISDWFDSLAEGLHWNVRKRQKCLDE 524
            ||.||:||||.:|.:||||:|||:.|||||||:|...:|
Human   545 TSCYPLPSICVRDPVSDWFESLAQCLHWNVRKKQAHFEE 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	209/414 (50%)
NADK	NP_001185923.1	DAGK_cat	<202..578	CDD:294771	209/414 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154612
Domainoid	1	1.000	359	1.000	Domainoid score	I969
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49724
Inparanoid	1	1.050	472	1.000	Inparanoid score	I1519
Isobase	1	0.950	-	0	Normalized mean entropy	S1835
OMA	1	1.010	-	-		QHG54603
OrthoDB	1	1.010	-	-		D1263874at2759
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		otm41553
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	LDO	PTHR20275
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720