DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6145 and nadkb

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_001073471.1	Gene:	nadkb / 562771	ZFINID:	ZDB-GENE-061103-433	Length:	472	Species:	Danio rerio

Alignment Length:	490	Identity:	252/490 - (51%)
Similarity:	320/490 - (65%)	Gaps:	54/490 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KRQRIIQHTANRASTRAKDQASTDDCVA-TSPGNIQAKSEQDPDDG------YFDSTTRRTRSGT 106
            :||:..|....:.....|......||.. .|.||:....||...:.      ..||..:|
Zfish    20 QRQQDRQGKLPKKRKEVKRSPRRPDCPEHLSGGNVHWLPEQQGSEASGSAEDTSDSCLKR----- 79

  Fly   107 WPRTRS---LNAPSPFQHFGPCGRIMKNSAMVMQIQDPASQRLTWYKPPLTVLVIKK-KDSQVLP 167
            |.|.|.   |:.|.|..||||...|:.|...||.|||||||||||.||||.||||:| :|..:|.
Zfish    80 WDRCRRGHFLHGPYPATHFGPKACILPNPTSVMHIQDPASQRLTWSKPPLNVLVIRKIRDETLLE 144

  Fly   168 PFVQLVEWLVQEKHMVVWVESAVLEDKLLRDDVKLEQESSKFQKVHQQYAGVRARFLDLREKLVT 232
            ||.:|..:||:|||::|:||..|::|..|..|     ||                |..:..:|.|
Zfish   145 PFKELCRFLVEEKHLMVYVEKKVVDDGSLMSD-----ES----------------FSAICNQLCT 188

  Fly   233 FKDGRDDLTDRIDFIVCLGGDGTLLYASQLFQQSVPPVMAFYLGSLGFLTPFQCDNFQEQVTNVL 297
            |::|.||::|.||.|:||||||||||||.|||.||||||||:||||||||||:.::|:.:|..|.
Zfish   189 FREGYDDISDCIDLIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFKFESFKTEVDKVF 253

  Fly   298 EGHAALTLRSRLRCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGSNNNNGH 362
            ||:||:.|||||:..: .||..::...|.:...|.::|.     |::   |.:.||.
Zfish   254 EGNAAIILRSRLKVKV-VKGMFQRNEQLFTTQENGVVPH-----NHI---NNEAGKI-------- 301

  Fly   363 NNSILVLNEVVINRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVP 427
            ...:.||||||::||||.||||:|::|:|:.||||||||:||||||||||||||||||||||:||
Zfish   302 TLQLQVLNEVVVDRGPSSYLSNVDLYLDGRLITSVQGDGVIVSTPTGSTAYAAAAGASMIHPNVP 366

  Fly   428 AILVTPICPHSLSFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVTTSIYPVP 492
            ||:||||||||||||||||||||||.|::|||:|||:.||||||..||:.||||:::|||.:|||
Zfish   367 AIMVTPICPHSLSFRPIVVPAGVELMITLSPDARNTAWVSFDGRKRQEIQHGDSIKITTSCFPVP 431

  Fly   493 SICSQDQISDWFDSLAEGLHWNVRKRQKCLDELSD 527
            |||..|.:.|||||||:.|||||||:|..|.:.||
Zfish   432 SICCHDLVYDWFDSLAQCLHWNVRKKQTRLTDASD 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	212/373 (57%)
nadkb	NP_001073471.1	DAGK_cat	<122..458	CDD:294771	212/373 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589806
Domainoid	1	1.000	353	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	461	1.000	Inparanoid score	I1533
OMA	1	1.010	-	-		QHG54603
OrthoDB	1	1.010	-	-		D1263874at2759
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		otm25729
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	O	PTHR20275
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770