DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6145 and CG33156

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_788346.1	Gene:	CG33156 / 36507	FlyBaseID:	FBgn0053156	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	552	Identity:	364/552 - (65%)
Similarity:	414/552 - (75%)	Gaps:	73/552 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LSDIDLATLHQHRLEEIFSYKLAWSGTGHQQTQYNDL----LVRHNASLKRQRIIQ--HTAN-RA 61
            ||||||||||::|||:.:.|.|..|...:.|..|:.:    :.|.......||.:|  |..| .|
  Fly     3 LSDIDLATLHENRLEQRWHYGLPNSHHIYHQHHYHHVGFSAMTRLCLERNLQRKVQPDHNGNCLA 67

  Fly    62 STRAKDQASTDDCVATSPGNIQAKSEQDPDDGYFDSTTRRTRSGTWPRTRSLNAPSPFQHFGPCG 126
            ..|:::.|:..|..::..|                   ||.||||||||||||||||.|.|||||
  Fly    68 RGRSRENANAIDSSSSGGG-------------------RRRRSGTWPRTRSLNAPSPVQQFGPCG 113

  Fly   127 RIMKNSAMVMQIQDPASQRLTWYKPPLTVLVIKK-KDSQVLPPFVQLVEWLVQEKHMVVWVESAV 190
            |||||||||||||||||||||||||||||||||| .|:.||.|||.||:||:|||:|||||||||
  Fly   114 RIMKNSAMVMQIQDPASQRLTWYKPPLTVLVIKKVSDASVLAPFVYLVDWLLQEKNMVVWVESAV 178

  Fly   191 LEDKLLRDDVKLEQESSKFQKVHQQYAGVRARFLDLREKLVTFKDGRDDLTDRIDFIVCLGGDGT 255
            |||..|.::|                     ||..:|:|||||||||||||||||||||||||||
  Fly   179 LEDVQLNENV---------------------RFKAIRDKLVTFKDGRDDLTDRIDFIVCLGGDGT 222

  Fly   256 LLYASQLFQQSVPPVMAFYLGSLGFLTPFQCDNFQEQVTNVLEGHAALTLRSRLRCSIHRKGERR 320
            |||||.||||||||||||:||||||||||:.|||:||:|:||||||||||||||||.:||:.:|:
  Fly   223 LLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRK 287

  Fly   321 KESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGSNNNNGHNNSILVLNEVVINRGPSPYLSNI 385
            .|:           .:.:..|      :|:...|.        |||||||||||:||||||||||
  Fly   288 HEA-----------KTLEADL------DGEARPAA--------NSILVLNEVVIDRGPSPYLSNI 327

  Fly   386 DIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAILVTPICPHSLSFRPIVVPAGV 450
            |:||:|||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
  Fly   328 DLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGV 392

  Fly   451 ELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVTTSIYPVPSICSQDQISDWFDSLAEGLHWNV 515
            |||||:||:|||||.|||||||.|||.|||||||||||||||.||:||||||||.|||:||||||
  Fly   393 ELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQISDWFASLADGLHWNV 457

  Fly   516 RKRQKCLDELSDLTTSGSEDTLDDFDNLQIYD 547
            ||||||||||||||.||||||||:.:|:::||
  Fly   458 RKRQKCLDELSDLTASGSEDTLDEIENMKLYD 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	269/373 (72%)
CG33156	NP_788346.1	DAGK_cat	<133..461	CDD:294771	269/373 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473044
Domainoid	1	1.000	238	1.000	Domainoid score	I599
eggNOG	1	0.900	-	-		E1_COG0061
Homologene	1	1.000	-	-		H49724
Inparanoid	1	1.050	276	1.000	Inparanoid score	I891
Isobase	1	0.950	-	0	Normalized mean entropy	S1835
OMA	1	1.010	-	-		QHG54603
OrthoDB	1	1.010	-	-		D1263874at2759
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		otm25729
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	P	PTHR20275
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2151
	14	13.760