DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6145 and SPAC3H5.11

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_594181.1	Gene:	SPAC3H5.11 / 2543649	PomBaseID:	SPAC3H5.11	Length:	393	Species:	Schizosaccharomyces pombe

Alignment Length:	465	Identity:	147/465 - (31%)
Similarity:	232/465 - (49%)	Gaps:	101/465 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 DDCVATSPGNIQAKSEQDPDDGYFDSTTRRTRSGTWPRTRSLNAPSPFQHFGPCGRIMKNSAMVM 136
            |.|:.|:|                  ||.....|::|.. |::| ..:.:...|        |||
pombe     6 DSCLPTNP------------------TTENDYHGSFPYC-SVHA-QLYPYVSDC--------MVM 42

  Fly   137 QIQDPASQR-----LTW-------------YKPPLT--VLVIKKKDSQVLPPFVQLVEWLVQEKH 181
            ..:.|.:::     :.|             .||.:|  :||.|..|.:|.....:.|.||:...:
pombe    43 HRKAPINEQEALRDVVWETRTINKKLHVTPIKPNITSILLVSKPGDEEVEEKLKEFVYWLISLDN 107

  Fly   182 MVVWVESAVLEDKLLRDDVKLEQESSKFQKVHQQYAGVRARFLDLREKLVTFKDGRDDLTDRIDF 246
            :.|:::.: :|| |.....|::..::.....|.|.                           .|.
pombe   108 ITVFIQKS-MED-LFEKTEKIQYWTTLLCTKHSQL---------------------------FDL 143

  Fly   247 IVCLGGDGTLLYASQLFQQSVPPVMAFYLGSLGFLTPFQCDNFQEQVTNVLE--GHAALTLRSRL 309
            ::.||||||:||.|:|||::|||:|.|.:|:|||||.|....::   |::||  ....:.||:|.
pombe   144 VLTLGGDGTVLYTSRLFQRTVPPIMPFAMGTLGFLTHFDVKKYK---TSILEICNEMYVHLRTRF 205

  Fly   310 RCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGSNNNNGHNNSILVLNEVVI 374
            .|.:.:|..|                   .|...::.:..|:..|.....:...:|::|||||||
pombe   206 ECRVMKKKNR-------------------TQWINIDEHLSQSLHATDTETHTFTDSLVVLNEVVI 251

  Fly   375 NRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAILVTPICPHSL 439
            :|||:..:|:|.::::.||:|:|:.|||.:|||||||||:.|||.|:.||.:..::|:|||.|||
pombe   252 DRGPNTAMSDIMLYVDSKYLTTVKADGLCISTPTGSTAYSLAAGGSLCHPDISVMIVSPICAHSL 316

  Fly   440 SFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVTTSIYPVPSICSQDQISDWF 504
            |.|||.||..:.|.:.|..|::.:|.:||||||..||..||.|.|..|.||.|::.|.::.:|||
pombe   317 SLRPIHVPDSMALHVVIPQDAQQSSWISFDGRNRTELLPGDYLTVRISRYPFPTVHSTEEDADWF 381

  Fly   505 DSLAEGLHWN 514
            :|:...|.||
pombe   382 ESIKRTLMWN 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	132/386 (34%)
SPAC3H5.11	NP_594181.1	NadF	80..391	CDD:223139	126/361 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	216	1.000	Domainoid score	I575
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49724
Inparanoid	1	1.050	240	1.000	Inparanoid score	I816
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		mtm9308
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	O	PTHR20275
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2151
TreeFam	1	0.960	-	-
	11	10.820