DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6145 and SPAC1B1.02c

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	NP_594232.1	Gene:	SPAC1B1.02c / 2542533	PomBaseID:	SPAC1B1.02c	Length:	537	Species:	Schizosaccharomyces pombe

Alignment Length:	555	Identity:	156/555 - (28%)
Similarity:	243/555 - (43%)	Gaps:	120/555 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ASLKRQRIIQHTAN---RASTRAKDQASTDDCVATSP------GNIQAKSEQDPDDG-------Y 94
            :.|........|.|   :..:|.||..:.|..|...|      .::...||..||:.       :
pombe     5 SKLSEDETFSQTFNEEEQEDSRNKDILAFDPSVDNEPLLTKKLSSLSIYSEPSPDEASNLQELKF 69

  Fly    95 FDS--TTRRTRSGTWPRTRSLNAPSPFQHFGPCGRIMKNSA---MVMQIQDPASQRL-TWY---- 149
            ..|  :.|..||....|...:::.:..:.|......:.||.   :.:|.|:.|..|. :.|
pombe    70 VSSPPSVRVPRSRRNRRNSRVDSEARKRQFDRVKHSVSNSCKLHLSLQGQEAAQLRSDSLYLEAS 134

  Fly   150 -KPPLTVLVIKKKD------------------------SQVLPPFVQLVEWLV------------ 177
             |..||.||.:.|:                        .:.:...|:|.:||:
pombe   135 DKRDLTSLVTRVKELARKLSAARLAFRFRKVLLICNDNKESIERSVELAQWLLDTFSFTPSSSHN 199

  Fly   178 -------QEKHMVVWVESAVLEDKLLRDDVKLEQESSKFQKVHQ--QYAGVRARFLDLREKLVTF 233
                   |....:..:||   |:|....||....|.:.|...:|  .|.......||:.|.|...
pombe   200 NMASSNTQSNTQLSEMES---EEKSFNKDVYPNDEYTPFTPKNQFVIYLEDTLASLDVVESLSPK 261

  Fly   234 KDGR-------DDLTDRIDFIVCLGGDGTLLYASQLFQQSVPPVMAFYLGSLGFLTPFQCDNFQE 291
            |:.|       ....:..|.::.:|.|...|.||.|||..||||::|.....|||:......:.:
pombe   262 KNVRFWTSELCTQCPNLFDCVITVGDDSAALRASWLFQDVVPPVLSFSTAKAGFLSILPIAEYTK 326

  Fly   292 QVTNVLEGHAALTLRSRLRCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGS 356
            .:..:......:.||.|.:|||.|                           ||          |.
pombe   327 TLDLIFHRGFTVNLRMRFQCSIMR---------------------------YV----------GE 354

  Fly   357 NNNNGHNNSILVLNEVVINRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGASM 421
            ::.:.......||||::|:|||:|::.::|:::|.:|||::|.||:.||||||||||:.|||.|:
pombe   355 HSTHICEGQYSVLNELLIDRGPNPFMISLDLYVENEYITTLQSDGVCVSTPTGSTAYSVAAGGSL 419

  Fly   422 IHPSVPAILVTPICPHSLSFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVTT 486
            .||.:||||::.|||||||||||::|..:.|:|.:..|:|:.:..:|||.:..||..||.:.::.
pombe   420 CHPGIPAILISAICPHSLSFRPIILPDSMTLRIVVPLDARSNAWCAFDGHHRIELGLGDYISISA 484

  Fly   487 SIYPVPSICSQDQISDWFDSLAEGLHWNVRK-RQK 520
            |.:|.||:.......||||.|.:.|:||.|| ||:
pombe   485 SSFPFPSVIRSKYSKDWFDILRQTLNWNDRKGRQR 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	129/431 (30%)
SPAC1B1.02c	NP_594232.1	NAD_kinase	165..492	CDD:279809	111/366 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		mtm9308
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	LDO	PTHR20275
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770