DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6145 and Nadk

DIOPT Version :9

Sequence 1:	NP_725314.1	Gene:	CG6145 / 36506	FlyBaseID:	FBgn0033853	Length:	548	Species:	Drosophila melanogaster
Sequence 2:	XP_038965017.1	Gene:	Nadk / 100125370	RGDID:	1642420	Length:	487	Species:	Rattus norvegicus

Alignment Length:	446	Identity:	231/446 - (51%)
Similarity:	294/446 - (65%)	Gaps:	63/446 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 RTRSLNAPSPFQHFGPCGRIMKNSAMVMQIQDPASQRLTWYKPPLTVLVIKK-KDSQVLPPFVQL 172
            |||||:.|.|...|||...:::|...:|.|||||||||||.|.|.:|||||| :|:.:|.||.:|
  Rat    93 RTRSLHGPCPVTTFGPKACVLQNPQTIMHIQDPASQRLTWNKSPKSVLVIKKIRDASLLQPFKEL 157

  Fly   173 VEWLVQEKHMVVWVESAVLEDKLLRDDVKLEQESSKFQKVHQQYAGVRARFLDLREKLVTFKDGR 237
            ..:|::|.:|:|:||..||||..:..|                     ..|..:::|..||::..
  Rat   158 CIYLMEENNMIVYVEKKVLEDPAIVGD---------------------ENFGPVKKKFCTFREDY 201

  Fly   238 DDLTDRIDFIVCLGGDGTLLYASQLFQQ-----------SVPPVMAFYLGSLGFLTPFQCDNFQE 291
            ||::::||||:||||||||||||.|||.           ||||||||:||||||||||..:|||.
  Rat   202 DDISNQIDFIICLGGDGTLLYASSLFQPGDATWSPHPQGSVPPVMAFHLGSLGFLTPFNFENFQS 266

  Fly   292 QVTNVLEGHAALTLRSRLRCSIHRKGERRKESLLHSVGGNLLIPSFQRQLNYVELNNGQTGKAGS 356
            ||..|:||:||:.|||||:..: .|..|.|::.:|                     ||.:.....
  Rat   267 QVNQVIEGNAAVILRSRLKVRV-VKEPRDKKTAIH---------------------NGLSENGLD 309

  Fly   357 NNNNGHNNSILVLNEVVINRGPSPYLSNIDIFLEGKYITSVQGDGLIVSTPTGSTAYAAAAGASM 421
            ...........|||||||:||||.||||:|::|:|..||:|||||:|||||||||||||||||||
  Rat   310 TEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDGVIVSTPTGSTAYAAAAGASM 374

  Fly   422 IHPSVPAILVTPICPHSLSFRPIVVPAGVELKISISPDSRNTSRVSFDGRNDQELNHGDSLRVTT 486
            :||:||||:||||||||||||||||||||||||.:||::|||:.||||||..||:.||||:.:||
  Rat   375 VHPNVPAIMVTPICPHSLSFRPIVVPAGVELKIMLSPEARNTAWVSFDGRKRQEIRHGDSISITT 439

  Fly   487 SIYPVPSICSQDQISDWFDSLAEGLHWNVRKRQKCLDELSDLTTSGSEDTLDDFDN 542
            |.||:||||..|.:||||:|||:.|||||||:|....|        .|:..|:.|:
  Rat   440 SCYPLPSICVCDPVSDWFESLAQCLHWNVRKKQAHFPE--------DEEDQDEEDS 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6145	NP_725314.1	DAGK_cat	<146..519	CDD:294771	206/384 (54%)
Nadk	XP_038965017.1	pnk	<128..472	CDD:333282	208/386 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348356
Domainoid	1	1.000	330	1.000	Domainoid score	I1119
eggNOG	1	0.900	-	-		E1_COG0061
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49724
Inparanoid	1	1.050	475	1.000	Inparanoid score	I1433
OMA	1	1.010	-	-		QHG54603
OrthoDB	1	1.010	-	-		D1263874at2759
OrthoFinder	1	1.000	-	-		FOG0001714
OrthoInspector	1	1.000	-	-		otm45674
orthoMCL	1	0.900	-	-		OOG6_100357
Panther	1	1.100	-	-	LDO	PTHR20275
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2151
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770