Protein Alignment mip120 and Lin54

DIOPT Version :10

• Sequence 1: NP_001163143.1
• Gene: mip120 / 36499
• FlyBaseID: FBgn0033846
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001415506.1
• Gene: Lin54 / 305171
• RGDID: 1311361
• Length: 767
• Species: Rattus norvegicus
• Alignment Length: 990
• Identity: 267/990 - (26%)
• Similarity: 378/990 - (38%)
• Gaps: 315/990 - (31%)

  Fly     9 LTDSLDDTEPLPELSFEDFLEPTSEKSSQHMEIEALDSEEDNIGGEDLADPAND------SLNTP 67
            |.|.:.||  ...|..||.:|.....|...||.|..:....|..|:..|.|.:.      |.:|.
  Rat    30 LPDDIMDT--AITLVDEDSIEAVIVSSPIPMETELEEIVSINSTGDSTATPISTEPITVYSNHTN 92

  Fly    68 QFKKNVVHILEDKRLNSSGLTVLKSHAIKMVTAGGTPPAKAQVTDVKILNKLKPIPSSTLKIGST 132
            |...|......|     |..||..:....:...|...|.......: ||||:.  .:|.||:|:.
  Rat    93 QVAVNTTVSKAD-----SNTTVKPAFPSGLQKLGAQTPVTISANQI-ILNKVS--QTSDLKLGNQ 149

  Fly   133 TIATKSTPGSITKTLGNLTQIRTKDGQVIFVQKSVPGTQSSTA--VTGSPSGGIRRLVAPSGIQK 195
            |:........:| |||       |.|..|.:  ::|.:|...|  ||.....|..:| .|..|
  Rat   150 TLKPDGQKLILT-TLG-------KSGSPIVL--ALPHSQLPQAQKVTAQAQPGDAKL-PPQQI-- 201

  Fly   196 AVLSKGVTMASTGLVKAAVPAKASTSVPGSAITLKGIQPLAGGTAKASTSSTTATTSPSLAQPNK 260
                |.||:.....||.|:...|.|  |||.:                   ...||.||:.|..:
  Rat   202 ----KVVTIGGRPEVKPAIGVSALT--PGSQL-------------------INTTTQPSVLQTQQ 241

  Fly   261 IQVVRTA-------DGKII-KINQAGPSLLVNAKQGTGTTVTPGGSAATSVKLSPS--TGNVVLN 315
            ::.|:.|       .|.:| |:..|.|   :|:|..||.|          .:.||.  ||.|:..
  Rat   242 LKTVQIAKKPRTPTSGPVITKLIFAKP---INSKAVTGQT----------TQASPPVVTGRVLSQ 293

  Fly   316 KPVGQVVVRTETPVKTAT--------GSVASASATPGKMLVQSGGKQILVSNKNIIKLSPNASAT 372
            ...|       ||.||.|        .::.|.:.||.|:.:..            :| |||.:..
  Rat   294 SAPG-------TPSKTITISESGVIGSTLNSTTQTPNKIAISP------------LK-SPNKTVK 338

  Fly   373 SST-THTTGGQTPS---------TSSGLHAIQLPGKGGIQYVRVLNNNKSAAGTSATASIPKTVQ 427
            |:. |.|.||.:.|         .:..:..||:|| ....|||::      ..|:|.:|.|...|
  Rat   339 SAVQTITVGGMSTSQFKTIIPLAAAPNVQPIQVPG-SKFHYVRLV------TATTAGSSAPPVSQ 396

  Fly   428 TQKITVVRPPAATGVPATSTTTSAAAASPAAASKANLAMGNTNKIVMRSMGGSIVPLPSVQTLVS 492
            :..:..  .|.....|....||....:.|...::|      ..::|.:       |:.|...:|:
  Rat   397 SPSVNT--QPLQQAKPVVVNTTPVRMSVPFVQAQA------VKQVVPK-------PINSTSQIVT 446

  Fly   493 KRALGAISNASKPASAASSSATPSASQELPR-KHRLTDLNVQLKQSASVSSEASDSSDAGPEAKK 556
                     .|:|.......|||     ||: :..||:|     ...:|.:.|..:.:.|.....
  Rat   447 ---------TSQPQQRLIMPATP-----LPQIQPNLTNL-----PPGTVLAPAPGTGNVGYAVLP 492

  Fly   557 PRYVITMQQGSQKAASQPVQKLINRTANVQRVVSSSTSPSSNSTKKIYNYVQPTGSNGAKYMICN 621
            .:||..:||                        ||..|.:.||     |:   ||::|.:
  Rat   493 AQYVTQLQQ------------------------SSYVSIAGNS-----NF---TGTSGIQ----- 520

  Fly   622 SGVPQSSTSAMRRGYTGYVENKTRRPPPISPQQHRFKQMGPQQQSKHQQLQAQAKQRIRQQQLPT 686
                   |.| |..:.|.:
  Rat   521 -------TQA-RVSFNGII---------------------------------------------- 531

  Fly   687 EQSTPIKVEPKLPTLPPGVKANVPAKPLFEVLKPPATAAAAGAVDPLGGMTSRRKHCNCSKSQCL 751
                            |...|:.|.||                             |||:||.||
  Rat   532 ----------------PSESASRPRKP-----------------------------CNCTKSLCL 551

  Fly   752 KLYCDCFANGEFCQDCTCKDCFNNLDYEVERERAIRSCLDRNPSAFKPKITAPNSGDM-RLHNKG 815
            |||||||||||||.:|.|.:|:|||::|.||::||::||||||.||||||.....|:. |.|:||
  Rat   552 KLYCDCFANGEFCNNCNCTNCYNNLEHENERQKAIKACLDRNPEAFKPKIGKGKEGESDRRHSKG 616

  Fly   816 CNCKRSGCLKNYCECYEAKIPCSSICKCVGCRNMEDRPD-VDMDSLDGLMGVEGQKKDKAKNK-- 877
            ||||||||||||||||||||.|||||||:||:|.|:.|: ..:..|.....|..|::..||.|
  Rat   617 CNCKRSGCLKNYCECYEAKIMCSSICKCIGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLS 681

  Fly   878 ------------QLNENRANIYF---TDDVIEATIMCMISRIVMHEKQNVAVEDMEREVMEEMGE 927
                        .||.....:.|   |.:|.|||..|::::....:|:..:....||.::||.|.
  Rat   682 SQISDLLTRPTPALNSGGGKLPFTFVTKEVAEATCNCLLAQAEQADKKGKSKAAAERMILEEFGR 746

  Fly   928 SLTQIIAFA-KEKQE 941
            .|..:|..| |.|.:
  Rat   747 CLMSVINSAGKAKSD 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mip120	NP_001163143.1	TCR	740..775	CDD:461001	23/34 (68%)
		TCR	813..850	CDD:461001	32/36 (89%)
Lin54	NP_001415506.1	None