DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf150 and rnf150

DIOPT Version :9

Sequence 1:	NP_001178022.1	Gene:	Rnf150 / 364983	RGDID:	1304572	Length:	437	Species:	Rattus norvegicus
Sequence 2:	NP_001135553.1	Gene:	rnf150 / 100216098	XenbaseID:	XB-GENE-5993052	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	438	Identity:	359/438 - (81%)
Similarity:	391/438 - (89%)	Gaps:	12/438 - (2%)

- Green bases have known domain annotations that are detailed below.

  Rat     1 MTMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYTEPESGAAVAGGGGGAE 65
            |.|||||||||||||||||||||||||||||||||||||||||||||||:|.|          .:
Frog     1 MAMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYTDPLS----------HQ 55

  Rat    66 LHTEKSECGRYGEHSPKQDARGEVVMASSVHDRLACDPNTKFAAPAHGKHWIALIPKGNCTYRDK 130
            ..|||||||||||||.||||.|..||.||..|||||||.|||:.||:...|:|||||||||||||
Frog    56 WRTEKSECGRYGEHSLKQDAWGLAVMPSSPQDRLACDPATKFSVPANASRWVALIPKGNCTYRDK 120

  Rat   131 IRNAFLQNASAVVIFNVG-SNTNETITMPHAGVEDIVAIMIPEPKGKELVSLLERNVTVTMYITI 194
            |::|.|||||||:|:||| ||.||||||||.|:|||||||||||||:|:.:|||||:.||:||||
Frog   121 IKHAALQNASAVLIYNVGSSNANETITMPHPGIEDIVAIMIPEPKGREIATLLERNINVTIYITI 185

  Rat   195 GTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQ 259
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Frog   186 GTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQ 250

  Rat   260 VRTIRKGDKETESDFDNCAVCIEGYKPSDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKA 324
            ||||:|||||||.:|||||||||||||:|||||||||||||||||||||||||||||||||||||
Frog   251 VRTIKKGDKETEPEFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKA 315

  Rat   325 LGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPAPQ 389
            |||||||||:||:|.|||||: ||||||||||||.|||||||.:||:|||||.|||:||.:..||
Frog   316 LGIPPNADCLDDIPPDFEGSV-GPPTNQITGASDVTVNESSVGIDPSVRTVGVLQVIQDAESLPQ 379

  Rat   390 EGEAIFTTNSDQEPAVSSDSDISLIMALEVGLSDVELSTDQDCEEVKS 437
            .||..:|.:|:||||||||||||||||::||||||:|||||||:|.||
Frog   380 VGEVSYTASSEQEPAVSSDSDISLIMAVDVGLSDVDLSTDQDCDEAKS 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf150	NP_001178022.1	PA_GRAIL_like	45..192	CDD:239037	100/147 (68%)
		UPF0233	<206..>231	CDD:299753	24/24 (100%)
		zf-RING_2	275..318	CDD:290367	41/42 (98%)
rnf150	NP_001135553.1	PA_GRAIL_like	45..183	CDD:239037	100/147 (68%)
		UPF0233	<197..>222	CDD:299753	24/24 (100%)
		zf-RING_2	266..309	CDD:290367	41/42 (98%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I15692
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H33783
Inparanoid	1	1.050	724	1.000	Inparanoid score	I4745
OMA	1	1.010	-	-		QHG50669
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		oto204748
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080