DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mars and Il1rapl2

DIOPT Version :9

Sequence 1:	NP_001163142.1	Gene:	mars / 36498	FlyBaseID:	FBgn0033845	Length:	921	Species:	Drosophila melanogaster
Sequence 2:	NP_109613.1	Gene:	Il1rapl2 / 60367	MGIID:	1913106	Length:	686	Species:	Mus musculus

Alignment Length:	176	Identity:	34/176 - (19%)
Similarity:	68/176 - (38%)	Gaps:	28/176 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EQSLVLSPRNHCQENRDRLQAARAKKREDCFY----QNRI----ISVSPTPV----------KIK 56
            |:.::.|.....:| .|.:....|::::..||    :|..    :|:|.|..          :|:
Mouse    84 EEPIIFSEVRMSKE-EDAIWFHSAEEQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIR 147

  Fly    57 QLAAAQAALTQENVAPKLESPERLDTKPAEL-LKESNPKVSRQKLYLQRYMEWKIAKTKEHKQQD 120
            .|..::....:|...|.::..::.|.:|..: .||..||:.| .:.:|:.....|       |:.
Mouse   148 YLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWR-SIIIQKGNALLI-------QEV 204

  Fly   121 QKRRGAAINVPTVKQSKALPKSQTFRVPDNLASAKQKEAAPMFQPP 166
            |:..|.........:.|.:.::...:|...|.....|...||...|
Mouse   205 QEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQP 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_001163142.1	GKAP	<558..>703	CDD:281368
Il1rapl2	NP_109613.1	Ig1_IL1RAPL-1_like	32..133	CDD:143304	10/49 (20%)
		Ig2_IL1R_like	146..237	CDD:319309	19/98 (19%)
		IG_like	250..347	CDD:214653	1/1 (100%)
		TIR	401..559	CDD:214587
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900