DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mars and il1rapl1a

DIOPT Version :9

Sequence 1:	NP_001163142.1	Gene:	mars / 36498	FlyBaseID:	FBgn0033845	Length:	921	Species:	Drosophila melanogaster
Sequence 2:	XP_021334418.1	Gene:	il1rapl1a / 568868	ZFINID:	ZDB-GENE-061013-249	Length:	1520	Species:	Danio rerio

Alignment Length:	490	Identity:	87/490 - (17%)
Similarity:	162/490 - (33%)	Gaps:	145/490 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 SQYTRLQDNVRKL-------------PQLKAELLHAATLDIPPLTPLDDIHNPFIDQATSTQCKS 426
            |:..:.|...|||             .:||..||....|..|      |.:.|||....::
Zfish   653 SKERKFQGTYRKLTPADWTTECQVAFDKLKTALLECVMLAHP------DFNEPFILSVDAS---- 707

  Fly   427 NNSSGHLLEAFGDTILLSPVAPVKAEGESSVKRQLLPEGKKEASGPVAKKKFDFTRYSVANSPAE 491
                   |:..|..:...|...::|...:...:.|....::.   |..:.:|...::||..   :
Zfish   708 -------LDGLGAVLSQVPKGELQARPIAFASKTLSTSQRRY---PAHRLEFMALKWSVCE---K 759

  Fly   492 DSLILDPQQTTVKEDTGDSTLVPEGTKTPPRRESNGMPNYLSPFVSVS------RGKVNSRCEKE 550
            .|..|...:.|:..|....|.:    .|.|:.::..: .::|...:.:      .||.|...:..
Zfish   760 FSHWLKGHKFTIWTDNNPLTYI----LTKPKLDAYEL-RWVSKLAAYTFDLKHLPGKANVVADTL 819

  Fly   551 KRNSF--------------YLSNEESPLEVRRAIESVLYFRL---------------QLENEITR 586
            .|:.|              ||..|.|.:. ..::..|  ||:               .::..:..
Zfish   820 SRDPFVEPIGRRLLNEPYSYLMQEASGIG-EDSVHDV--FRVSSHIQPNQPMECLSQSVDYNVDE 881

  Fly   587 LQALCAEWEAYSKENEAR-LQETGGIDMIN-------------VTIGQTRLLTTKKMMQFSGLID 637
            ::|||....:::...|:| |.....:.||:             :...|...||..|::.|  ||
Zfish   882 VKALCQSHCSWTDGAESRALHLVHHVQMISGCQETLPVLSAQELKDSQQEDLTISKVLSF--LI- 943

  Fly   638 RCEAGATGKNSQPNDGSEDSKPVQAEDLEGWWDMLRLQSE---NVDKRFDNLKRWKANDWLDPDA 699
                    :..:|:.........|...|...|..|.::.:   .|.|  |.|.:.|...::.||:
Zfish   944 --------RQRRPSRRERHGASAQVIRLLKQWSKLEVRDDVLYRVTK--DPLTKRKRLQYVLPDS 998

  Fly   700 VAEE--------------------PKQPKPKPKISRNMK----------IKSKAKPSSNLQQFLR 734
            :..:                    .:|....|.:.:|::          :....:|::      |
Zfish   999 LRNKALSGIHDLAGHQGQDRTISLARQRFYWPDMEKNIREYVQCCRRCVLAKSPEPAA------R 1057

  Fly   735 KAHANMKKTKVEEPTLEDGLPATSSRHSSPRVIVV 769
            ....|:|.|...|....|...|.:|:..|..|:||
Zfish  1058 APLENIKSTAPMELVCIDFWSAENSKQCSVDVLVV 1092

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_001163142.1	GKAP	<558..>703	CDD:281368	32/176 (18%)
il1rapl1a	XP_021334418.1	retropepsin_like	46..137	CDD:133136
		RT_LTR	403..579	CDD:238825
		RNase_HI_RT_Ty3	701..823	CDD:260006	22/143 (15%)
		rve	1068..1176	CDD:307008	8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900