Protein Alignment mars and dlgap4a

DIOPT Version :10

• Sequence 1: NP_610878.1
• Gene: mars / 36498
• FlyBaseID: FBgn0033845
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_073795524.1
• Gene: dlgap4a / 562742
• ZFINID: ZDB-GENE-080219-51
• Length: 1034
• Species: Danio rerio
• Alignment Length: 943
• Identity: 184/943 - (19%)
• Similarity: 291/943 - (30%)
• Gaps: 359/943 - (38%)

  Fly    72 PKLESPERLDTKPAELLKESNPKVSRQKLYLQRYMEWKIAKTKEHKQQDQKRRGAAINVPTVKQS 136
            |:.|||.|:          .|...|.|||:         ||::..:....|.........|.::|
Zfish   181 PRSESPSRI----------RNLVQSVQKLF---------AKSQSLEVSAIKAGSITSGDKTGRRS 226

  Fly   137 KALPKSQT----FRVPDNLASAKQKEAAPMFQPPKRCSLYMIANPTGKGKAAEPIKPSIPKPTSA 197
            |:..:::|    .|...||:.....:......||        |.||     |.|:..:...|.|.
Zfish   227 KSKDRAKTEGTKRRPRPNLSGFWSSDDGLEDDPP--------AQPT-----AGPLAVAYRNPLSM 278

  Fly   198 AA---------------PPSSNTVAA---SSALARHKSAASATKIVPAIRQNNNPV--------- 235
            ..               |...||:||   |.:....|:.||   :.||..|:...|
Zfish   279 MTLGRAVSDSQAALKPHPQGYNTIAALKSSKSSGELKAQAS---LPPAGAQHAELVKRGSWSTLT 340

  Fly   236 -ALAR---QKAAARPIPNTTKQTTSVRQPGIEAKKITTTI------------------------- 271
             :.||   ||::|      |...|.::......:::|...
Zfish   341 LSQARQVLQKSSA------TVNRTLLKSKSCHGQEMTCNFLQVPTGEWSGTLGKAGAAGEIPCRR 399

  Fly   272 ------------------------PRPTPATVTKAKTPGIRQQPPVVSTKPRLPE--PPAPRTAR 310
                                    |:|:|.:..       |:|..:.:|:..|.|  ||.|....
Zfish   400 MRSGSYVKAMGDTEDSEDSDGPPSPKPSPKSAA-------RRQSYLKATQHSLSEQQPPLPPRNC 457

  Fly   311 LPNVLSKPFEKPLGNKAPVTRRANVVKPQPIRGGGGAAAKFKDTAGATSKAASHSIRMKATKIKS 375
            :|::...|..:.|.|.            ..:.|.|.||.:..|..|..|:..:   .:....|.|
Zfish   458 MPSLCEVPTNRSLDNL------------DCLMGPGDAALQHWDVDGGFSQRCA---TLGRGSIMS 507

  Fly   376 QYTRLQDNVRKLPQLKAELLHAATL---------------------------------DIPPLT- 406
            |..:.........||:::.:.|..|                                 :.||:|
Zfish   508 QVEQCFMASAAYGQLESQAVEALDLPTPTCFRSRSHSYLRAIQAGCSQDEDTGSVDSDETPPITS 572

  Fly   407 ------------------------PLDDIHNPFI-------------------DQATSTQCKS-- 426
                                    |..:...|:|                   ||.:....:|
Zfish   573 SISSCNSVTVSTCTAVCKKNPPPVPPRNASKPYISVTVQSSTESAQDTYLDSQDQRSEVNSQSGR 637

  Fly   427 NNSS--------GHLLEAFGDTILLSPV--------------------------AP--------- 448
            :|||        |.|::......:|.|:                          ||
Zfish   638 SNSSDSLASSRTGSLVKGSKRPPILPPIPAPREPVQLPSARVTTPPPAIAPPTPAPDAKPQPLSL 702

  Fly   449 --VKAEGESSVKRQLLPEG-KKEASGPVAK-KKFDFTRYSVANSPAED-------SLILDPQQTT 502
              |..|.::..||:|...| :.:...|:.| ::...||:.......||       :.:...|:||
Zfish   703 TLVPDEPQAPPKRKLSSIGIQVDCVQPILKEEQTPTTRFQSIGVQVEDGRPLSRFTSMASRQETT 767

  Fly   503 VKEDTGDSTLVPEGTKTP------------PRRESNGMPNYLSPFVSVSR------------GKV 543
            ..|....|.....|.|||            .|..|..:...|.|.:..||            |.|
Zfish   768 EAESQEQSDGKHLGNKTPGQSLDKPSLADMTRSASTSLQEKLDPALDPSRLPPPDPSLQSGSGSV 832

  Fly   544 N--------SRCEKEKRNSFYLSNEESPLEVRRAIESVLYFRLQLENEITRLQALCAEWEAYSKE 600
            |        |.|.::.|                      .|:..|:.|..|::|.|.:.|..:|:
Zfish   833 NGAVEQLGGSACLRDGR----------------------CFQKLLQAETDRMEAWCQQMEEETKD 875

  Fly   601 NEARLQETGGIDMINVTIGQTRLLTTKKMMQFSGLIDRCEAGATGKNSQPNDGSEDSKPVQAEDL 665
            .:...:..|   .|...:|..:||.::|..||.||   ||        |..|.|...:|. |:||
Zfish   876 KQLSEEVLG---KIRSAVGSAQLLMSQKFRQFQGL---CE--------QNLDVSAQPRPT-AQDL 925

  Fly   666 EGWWDMLRLQSENVDKRFDNLKRWKANDWLDPDAVAEEPKQPKPKPKISRNMKIKSKAKPSSNLQ 730
            .|:||:|:|..|::..:||.|...::|||...|...|:...|...||  :.:|:|.......:|.
Zfish   926 AGFWDLLQLSIEDISMKFDELHLLRSNDWKTTDKKEEKKSAPSHTPK--KTVKVKPSGGKEKSLD 988

  Fly   731 QFLRKAHANMKKTKVEEPTLEDGLPATSSRHSS 763
            ....|.....:|      .|.....|.|.|.:|
Zfish   989 SVADKQRQEARK------RLMAAKRAVSERQNS 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_610878.1	PHA03247	<131..342	CDD:223021	52/296 (18%)
		GKAP	<580..>694	CDD:460897	36/113 (32%)
dlgap4a	XP_073795524.1	None