DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mars and Il1rapl1

DIOPT Version :9

Sequence 1:	NP_001163142.1	Gene:	mars / 36498	FlyBaseID:	FBgn0033845	Length:	921	Species:	Drosophila melanogaster
Sequence 2:	NP_001153875.1	Gene:	Il1rapl1 / 331461	MGIID:	2687319	Length:	696	Species:	Mus musculus

Alignment Length:	193	Identity:	40/193 - (20%)
Similarity:	59/193 - (30%)	Gaps:	71/193 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   711 PKISRNMKIKSKAKPSSNLQQFLRKAHANMKKTKVEEPTLEDGLPATSSRHSSPRVIVVRNRRSF 775
            ||.:   |:.||         |.::....|...::|..|.|..|.             |..:..|
Mouse   542 PKCN---KLNSK---------FWKRLQYEMPFKRIEPITHEQALD-------------VSEQGPF 581

  Fly   776 SPARTVLRMSTGEGRQSIAPNALLKSAILAAAEQNAAKTPPPKPRTSILKTPGTTKRQNRGVLFS 840
            ...:||..:|                  :|||...|..|..|..|::...|..:..||
Mouse   582 GELQTVSAIS------------------MAAATSTALATAHPDLRSTFHNTYHSQMRQ------- 621

  Fly   841 AKKSVRRFQF------TYEEGNISNDETVGADKLEDCEEDMSLEASTESGSLEQNPGRDSNQE 897
             |...|.:::      |....:|.|..|.       |...|:|...       |.|...||:|
Mouse   622 -KHYYRSYEYDVPPTGTLPLTSIGNQHTY-------CNIPMTLING-------QRPQTKSNRE 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_001163142.1	GKAP	<558..>703	CDD:281368
Il1rapl1	NP_001153875.1	PHA02785	9..334	CDD:165149
		Ig1_IL1RAPL-1_like	32..135	CDD:143304
		Ig	148..234	CDD:299845
		IGc2	260..341	CDD:197706
		TIR	405..559	CDD:279864	6/28 (21%)
		Interaction with NCS1. /evidence=ECO:0000250	549..644		26/142 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	658..680		5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900